This enzyme is soluble in 50 mM potassium phosphate buffer at 1 mg/mL, yielding a clear solution. Please see the link below to review the product datasheet:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/134/883/x4376pis.pdf
X4376
Xanthine Oxidase from bovine milk
lyophilized powder, 0.4-1.0 units/mg protein
동의어(들):
XOD, Xanthine:oxygen oxidoreductase
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모든 사진(3)
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5 UNITS
₩257,607
25 UNITS
₩889,749
50 UNITS
₩1,595,377
About This Item
CAS Number:
효소 위원회 번호:
1.17.3.2.
EC Number:
MDL number:
UNSPSC 코드:
12352204
NACRES:
NA.54
추천 제품
일반 설명
Formerly E.C. 1.1.3.22
애플리케이션
생화학적/생리학적 작용
The isoflavanoid genistein was shown to inhibit xanthine oxidase at concentrations between 0.1-4.0 μM and then activate xanthine oxidase at concentrations higher than 5 μM. [4]
Xanthine Oxidase acts as a potential biomarker for oxidative stress. It is also implicated in tissue and vascular injuries such as liver damage, inflammatory diseases and chronic heart failure.[3]
Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids. It plays a vital role in the metabolism of some drugs, as well as purines and pyrimidines. It is also known to be a biological source of reactive oxygen species.
단위 정의
One unit will convert 1.0 μmole of xanthine to uric acid per min at pH 7.5 at 25 °C. Approx. 50% of the activity is obtained with hypoxanthine as substrate.
물리적 형태
Contains 0.5% sodium salicylate.
분석 메모
Protein determined by biuret
신호어
Danger
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Resp. Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
Genistein effect on xanthine oxidase activity.
Sumbayev VV.
Food And Chemical Toxicology, 73, 39-43 (2001)
Rokshana Sharmin et al.
ACS sensors, 6(12), 4349-4359 (2021-11-20)
Free-radical generation is suspected to play a key role in cardiovascular diseases. Another crucial factor is shear stress. Human umbilical vein endothelial cells (HUVECS), which form the lining of blood vessels, require a physiological shear stress to activate many vasoactive
Massimiliano Magro et al.
Materials (Basel, Switzerland), 13(7) (2020-04-16)
Generally, enzyme immobilization on nanoparticles leads to nano-conjugates presenting partially preserved, or even absent, biological properties. Notwithstanding, recent research demonstrated that the coupling to nanomaterials can improve the activity of immobilized enzymes. Herein, xanthine oxidase (XO) was immobilized by self-assembly
Rapid electrochemical enzyme assay with enzyme-free calibration
Zhang M, et al.
Analytical Chemistry, 85(12), 6026-6032 (2013)
Resistance of postharvest biocontrol yeasts to oxidative stress: a possible new mechanism of action
Castoria R, et al.
Phytopathology, 93(5), 564-572 (2003)
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Good morning, I have a question how to use Xanthine Oxidase in the form lyophilized powder? In what form can it be used? Can it be converted into a liquid form? If so, what should be the solvent? Should I use water or buffer? If a buffer witch one?
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