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Merck
모든 사진(4)

문서

X4002

Sigma-Aldrich

Xanthine

BioUltra, ≥99%

동의어(들):

2,6-Dihydroxypurine

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About This Item

실험식(Hill 표기법):
C5H4N4O2
CAS Number:
Molecular Weight:
152.11
Beilstein:
8733
EC Number:
MDL number:
UNSPSC 코드:
41106305
PubChem Substance ID:
NACRES:
NA.51

생물학적 소스

synthetic (organic)

제품 라인

BioUltra

분석

≥99%

형태

powder

불순물

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

무기 잔류물

≤0.1%

solubility

1 M NaOH: 0.1 M, clear, colorless to light yellow

음이온 미량물

sulfate (SO42-): <0.05%

양이온 미량물

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES string

O=C1NC(=O)c2nc[nH]c2N1

InChI

1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)

InChI key

LRFVTYWOQMYALW-UHFFFAOYSA-N

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일반 설명

Xanthine is a purine that can be produced in the purine metabolic pathway via different precursors:
  • Guanine deamination by guanine deaminase
  • Hypoxanthine conversion by xanthine oxidoreductase
Xanthine or its derivatives are naturally present in animal organs, yeast, potatoes, coffee beans, and tea.

애플리케이션

Xanthine has been used as a substrate for the determination of xanthine oxidase (XOD) inhibitory activity. It has also been used in the following systems:
  • yeast culture
  • human cell line culture
  • recombinant viruses cloned as bacterial artificial chromosomes in Escherichia coli

생화학적/생리학적 작용

Xanthine and xanthine oxidase are used to generate superoxide radicals to measure the activity of superoxide dismutase.

특징 및 장점

  • Tested for trace metal content (fuller details in Properties section and on Specification Sheet)
  • Tested for trace sulfate content (fuller details in Properties section and on Specification Sheet)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

개인 보호 장비

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

Raffaello Castoria et al.
Phytopathology, 93(5), 564-572 (2008-10-24)
ABSTRACT We detected the generation of the reactive oxygen species (ROS) superoxide anion ( O.(-) (2)) and hydrogen peroxide (H(2)O(2)) in apple wounds 2 immediately after wounding, and assessed the relationships between (i) timely colonization of apple wounds by biocontrol
Insights from multispectral and molecular docking investigation on the xanthine oxidase inhibition by 1, 4-dicaffeoylquinic acid
Cao W, et al.
Journal of Molecular Structure, 1219, 128475-128475 null
Optimization of total phenolic contents, antioxidant, and in-vitro xanthine oxidase inhibitory activity of sunflower head
Mehmood A, et al.
CYTA-journal of Food, 16, 957-964 null
Avery G Frey et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(22), 8031-8036 (2014-05-21)
Although cells express hundreds of metalloenzymes, the mechanisms by which apoenzymes receive their metal cofactors are largely unknown. Poly(rC)-binding proteins PCBP1 and PCBP2 are multifunctional adaptor proteins that bind iron and deliver it to ferritin for storage or to prolyl
S M Forget et al.
Organic & biomolecular chemistry, 13(3), 866-875 (2014-11-20)
Cps2L, a thymidylytransferase, is the first enzyme in Streptococcus pneumoniae L-rhamnose biosynthesis and an antibacterial target. We herein report the evaluation of six sugar phosphate analogues selected to further probe Cps2L substrate tolerance. A modified continuous spectrophotometric assay was employed

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