콘텐츠로 건너뛰기
Merck
모든 사진(2)

주요 문서

모든 문서 보기

860646P

Avanti

C18 Ceramide (d17:1/18:0)

Avanti Research™ - A Croda Brand 860646P, powder

동의어(들):

N-stearoyl-D-erythro-sphingosine (C17 base)

로그인조직 및 계약 가격 보기
모든 사진(2)

About This Item

실험식(Hill 표기법):
C35H69NO3
CAS Number:
123065-42-9
Molecular Weight:
551.93
UNSPSC 코드:
12352211
NACRES:
NA.25

양식

powder

포장

pkg of 1 × 10 mg (860646P-10mg)

제조업체/상표

Avanti Research™ - A Croda Brand 860646P

지질 유형

sphingolipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCC

InChI key

KGEXFGDEDXQZLQ-QKSCFGQVSA-N

일반 설명

Ceramide is a bioactive sphingolipid. C18 Ceramide (d17:1/18:0) is synthesized by the N-acylation of sphingosine.[1] This reaction is catalyzed by ceramide synthase 1 (CerS1).[2] C18 Ceramide is highly expressed in brain tissues.[1]

애플리케이션

C18 Ceramide (d17:1/18:0) has been used as an internal standard in mass spectrometer and ultra high performance Liquid Chromatography for quantitative measurement of ceramides in muscle.[3]

생화학적/생리학적 작용

C18 Ceramide has an ability to induce cell death.[4] Defects in the generation or accumulation of C18 Ceramide has been associated with the development of human head and neck squamous cell carcinomas (HNSCC).[2]

포장

5 mL Amber Glass Screw Cap Vial (860646P-10mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 문서 section.

도움이 필요하시면 연락하세요. 고객 지원 부서

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): attenuation of C18-ceramide in HNSCC tumors correlates with lymphovascular invasion and nodal metastasis
Karahatay S, et al.
Cancer Letters, 256(1), 101-111 (2007)
Long-term follow-up of muscle lipid accumulation, mitochondrial activity and oxidative stress and their relationship with impaired glucose homeostasis in high fat high fructose diet-fed rats
Wang Y, et al.
The Journal of Nutritional Biochemistry, 64(5), 182-197 (2019)
Koichi Ishida et al.
The Journal of investigative dermatology (2020-02-06)
Little is known about the pathophysiological linkages between altered ceramide profiles in the stratum corneum (SC) of patients with atopic dermatitis and their impaired skin barrier and water-holding functions. We studied those characteristics following topical treatment with a designed synthetic
Diverse functions of ceramide in cancer cell death and proliferation
Advances in Cancer Research, 117, 37-58 (2013)
The structure of D-erythro-C18 ceramide at the air-water interface
Vaknin D and Kelley MS
Biophysical Journal, 79(5), 2616-2623 (2000)
모든 관련된 서류 보기

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.