S3699

Anti-SEL1L (N-terminal) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

• 別名: Anti-SEL1-like, Anti-Sel-1 suppressor of lin-12-like (C. elegans), Anti-Suppressor of lin-12-like
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: antigen ~100 kDa
• 交差性: human
• 濃度: ~1.0 mg/mL
• テクニック: immunoprecipitation (IP): 2-5 μg using lysate of human MCF-7 cells; indirect immunofluorescence: 2-4 μg/mL; western blot: 0.5-1.0 μg/mL using whole extracts of human MCF-7 cells
• UniProtアクセッション番号: Q9UBV2
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... SEL1L(6400)

詳細

詳細

SEL1L (Sel-1-like) is a type I transmembrane glycoprotein, that is located in ER (endoplasmic reticulum). It is considered as a putative tumor suppressor gene. It is located on chromosome 14q.

SEL1L is highly expressed in the pancreas.

アプリケーション

Anti-SEL1L (N-terminal) antibody produced in rabbit has been used in

• immunoblotting
• immunoprecipitation
• immunofluorescence

生物化学的／生理学的作用

SEL1L (Sel-1-like) participates in the degradation pathway linked with endoplasmic reticulum (ER), malignant transformation and stem cells. It helps in the self regeneration of the neural stem cell. It controls cell fate developmental decision and homeostasis. It plays an important role in retaining homeostasis of endoplasmic reticulum throughout embryonic growth of vertebrate.

SEL1L is involved in cell growth and cancer progression.

物理的形状

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)