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Merck

SIRNA

MISSION® siRNA Product Offerings

Custom and Predesigned siRNA

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Custom siRNA

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12352208

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Slide 1 of 4

1 of 4

Fuhui Xu et al.
PloS one, 9(9), e106509-e106509 (2014-09-04)
Improved drought tolerance is always a highly desired trait for agricultural plants. Significantly increased drought tolerance in Arabidopsis thaliana (Columbia-0) has been achieved in our work through the suppression of ESKMO1 (ESK1) gene expression with small-interfering RNA (siRNA) and overexpression
Antonis C Antoniou et al.
The New England journal of medicine, 371(6), 497-506 (2014-08-08)
Germline loss-of-function mutations in PALB2 are known to confer a predisposition to breast cancer. However, the lifetime risk of breast cancer that is conferred by such mutations remains unknown. We analyzed the risk of breast cancer among 362 members of
Chong He et al.
PLoS genetics, 10(12), e1004860-e1004860 (2014-12-19)
The common non-steroidal anti-inflammatory drug ibuprofen has been associated with a reduced risk of some age-related pathologies. However, a general pro-longevity role for ibuprofen and its mechanistic basis remains unclear. Here we show that ibuprofen increased the lifespan of Saccharomyces
Maria Dermit et al.
Developmental cell, 55(3), 298-313 (2020-11-11)
Translation of ribosomal protein-coding mRNAs (RP-mRNAs) constitutes a key step in ribosome biogenesis, but the mechanisms that modulate RP-mRNA translation in coordination with other cellular processes are poorly defined. Here, we show that subcellular localization of RP-mRNAs acts as a
Yanli Ma et al.
PloS one, 7(10), e47961-e47961 (2012-11-01)
Aflatoxin B1 (AFB1) is a potent carcinogen that can induce hepatocellular carcinoma. AFB1-8,9-exo-epoxide, one of AFB1 metabolites, acts as a mutagen to react with DNA and induce gene mutations, including the tumor suppressor p53. In addition, AFB1 reportedly stimulates IGF

資料

次世代シーケンシング(NGS)プラットフォームだけでなく、サンプルフラグメントの適切なアセンブリには、ユニバーサルアダプターとインデックスアダプターが必要です。

関連コンテンツ

Use our synthetic, small interfering RNA (siRNA) duplex plates to identify gene function, elucidate pathways, and screen for potential new drug targets.

LightCycler probes are highly sensitive and sequence-specific fluorescent probes designed for use with the Roche LightCycler instruments.

We can quickly synthesize and ship custom siRNA using your sequences.

遺伝子機能の同定、経路の解明、新規創薬標的候補の探索には、メルクの合成低分子干渉RNA(siRNA)プレートをお使いください。

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ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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