D9150
2,3-ジメトキシ-5-メチル-p-ベンゾキノン
apoptosis inducer
別名:
コエンザイムQ0
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| あなたへ/カタログ番号 | 在庫状況 | 単価 |
|---|---|---|
1 g | カートの在庫状況を確認する | ￥12,800 |
5 g | カートの在庫状況を確認する | ￥40,000 |
この商品について
実験式（ヒル表記法）:
C9H10O4
CAS番号:
分子量:
182.17
UNSPSC Code:
12352204
NACRES:
NA.51
PubChem Substance ID:
EC Number:
210-100-8
Beilstein/REAXYS Number:
1640422
MDL number:
￥12,800
カートの在庫状況を確認する
高品質はそのまま、さらにお手頃な価格になりました
Quality Segment
form
powder
mp
58-60 °C (lit.)
storage temp.
2-8°C
SMILES string
COC1=C(OC)C(=O)C(C)=CC1=O
InChI
1S/C9H10O4/c1-5-4-6(10)8(12-2)9(13-3)7(5)11/h4H,1-3H3
InChI key
UIXPTCZPFCVOQF-UHFFFAOYSA-N
General description
2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q0 or DMM) is present in all the cells including neural cells.[1]
Application
2,3-Dimethoxy-5-methyl-p-benzoquinone has been used:
- as a tau protein fibrillization inducer to determine the regions of tau involved in the formation of paired helical filaments (PHFs)
- as a component in buffer B for cytochrome oxidation assay with subsaturating light
- in the RPMI-1640 medium for 2,3-bis-(2-methoxy-4-nitro-5-sulphenyl)-(2H)-tetrazolium-5-carboxanilide (XTT) assay to quantify antifungal activity
Coenzyme Q0 inhibits (via radical quenching) reactions of gamma-irradiation induced homolytic cleavage of O-glycoside bonds in polysaccharides. Coenzyme Q0 induces apoptosis and modulates the cell cycle in estrogen receptor negative breast cancer cells. It is toxic to other cells such as insulin producing cells.
Biochem/physiol Actions
2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q0) interacts with tau protein and aids in the formation of filamentous structure.[1]
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当該品目 | |||
|---|---|---|---|
| form powder | form - | form solid | form solid |
| storage temp. 2-8°C | storage temp. - | storage temp. - | storage temp. - |
| Quality Level 200 | Quality Level 100 | Quality Level 200 | Quality Level 200 |
| mp 58-60 °C (lit.) | mp 253-257 °C (dec.) (lit.) | mp 66-67 °C (lit.) | mp 54-58 °C (lit.) |
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
保管分類
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves