A271

Anti-α_2A Adrenergic Receptor antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 別名: Anti-ADRA2, Anti-ADRA2R, Anti-ADRAR, Anti-ALPHA2AAR, Anti-ZNF32
• MDL番号: MFCD01321639
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: antigen ~45 kDa
• 交差性: rat, human, mouse, pig
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:1000; western blot: 1:500
• UniProtアクセッション番号: P08913
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ADRA2A(150) ; mouse ... Adra2a(11551) ; rat ... Adra2a(25083)

詳細

詳細

Adrenergic receptors (ARs) belong to the 7-transmembrane domain G protein-coupled receptor superfamily that binds to the endogenous catecholamines, epinephrine and norepinephrine. α₂AR subtypes block adenylyl cyclase, suppress voltage-sensitive Ca²⁺ channels, and stimulate receptor dependent K⁺ channels. All of the α₂AR subtypes inhibit adenylyl cyclase through coupling to members of the G_i/G_o class of G proteins. They are an important component of the neural circuitry and modulate cardiovascular physiology. The physiological function of the α₂ARs in the kidney is to regulate Na⁺/H⁺ exchange.
Anti-α_2A adrenergic receptor detects rat and mouse α_2A adrenergic receptors by immunoblotting and immunohistochemistry. In immunoblotting, the antibody detects an approx. 45kDa band representing α_2A receptors in tissues expressing this receptor subtype, although some non-specific bands have also been observed in certain cases.

免疫原

ヒト, マウス, ラット, ブタα_2Aアドレナリンレセプタ-のアミノ酸218-235に由来する合成ペプチド。免疫原の配列は、α_2Aアドレナリンレセプタ-の細胞内第三ル-プ内に存在しています。

アプリケーション

Rabbit anti-α_2A adrenergic receptor antibody can be used for western blot (1:500) and immunohistochemistry (1:1000) applications.

物理的形状

PBS溶液(1 mg/mL BSA, 0.05%アジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)