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Merck

78780

Sigma-Aldrich

イソチオシアン酸フェニル

for HPLC derivatization, the detection of alcohols and amines, ≥99.0%

別名:

PITC

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25 ML
¥8,790
100 ML
¥18,900
500 ML
¥66,500

¥8,790


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25 ML
¥8,790
100 ML
¥18,900
500 ML
¥66,500

About This Item

化学式:
C6H5NCS
CAS番号:
分子量:
135.19
Beilstein:
471392
EC Number:
MDL番号:
UNSPSCコード:
12352100
PubChem Substance ID:
NACRES:
NA.21

¥8,790


Check Cart for Availability

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品質水準

アッセイ

≥99.0%

フォーム

liquid

品質

for HPLC derivatization, the detection of alcohols and amines

屈折率

n20/D 1.649
n20/D 1.6515 (lit.)

bp

218 °C (lit.)

mp

−21 °C (lit.)

溶解性

water: insoluble

密度

1.13 g/mL at 20 °C
1.132 g/mL at 20 °C (lit.)

保管温度

2-8°C

SMILES記法

S=C=Nc1ccccc1

InChI

1S/C7H5NS/c9-6-8-7-4-2-1-3-5-7/h1-5H

InChI Key

QKFJKGMPGYROCL-UHFFFAOYSA-N

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詳細

Phenyl isothiocyanate is an aromatic isothiocyanate. It participates in dehydration reactions of alcohols.[1] It is widely used for synthesis of various biologically important heterocyclic compounds.[2]

アプリケーション

第1級及び第2級アミンの誘導体化試薬。エドマン分解によるペプチドシークエンシング及びHPCLによるアミノ酸分析に用いられます。
Phenyl isothiocyanate may be employed as a derivatization reagent for high-performance liquid chromatographic (HPLC) analysis of various amphetamine derivatives in body fluids.[3]

注意

Store under Argon

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ピクトグラム

Skull and crossbonesHealth hazardCorrosion

シグナルワード

Danger

危険有害性情報

危険有害性の分類

Acute Tox. 3 Oral - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1

保管分類コード

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

引火点(°F)

190.4 °F - closed cup

引火点(℃)

88 °C - closed cup

個人用保護具 (PPE)

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

消防法

第4類:引火性液体
第三石油類
危険等級III
非水溶性液体

Jan Code

78780-INTR:
78780-100ML:
78780-BULK:
78780-VAR:
78780-25ML:
78780-500ML:


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Determination of phenylisothiocyanate derivatives of amphetamine and its analogues in biological fluids by HPLC-APCI-MS or DAD.
Bogusz MJ, et al.
Journal of Analytical Toxicology, 21(1), 59-69 (1997)
One-pot dehydrations using phenyl isothiocyanate.
Majetich G, et al.
Tetrahedron Letters, 56(23), 3326-3329 (2015)
Amin Zolali et al.
Combinatorial chemistry & high throughput screening, 17(7), 610-613 (2014-03-19)
An efficient, one-pot and three-component synthesis of biologically important heterocyclic compounds is described from the reaction of primary amines and phenyl isothiocyanate in the presence of acryloyl chloride at room temperature without the need to use any catalyst.
Tomoyuki Oe et al.
Rapid communications in mass spectrometry : RCM, 24(2), 173-179 (2009-12-17)
This manuscript describes the results of a preliminary experiment performed as 'proof of concept' of a novel approach to absolute quantitation of proteins without the use of standard proteins. Absolute quantitation remains a challenging issue in the proteomics field. Therefore
Akira Murakami et al.
BioFactors (Oxford, England), 30(1), 1-11 (2008-01-17)
Osteoclastogenesis is induced by differentiation of hemopoietic cells of monocyte-macrophage lineage into bone-resorbing osteoclasts. The process is initiated by receptor activator of NF-kappaB ligand (RANKL) and resultant activation of mitogen-activated protein kinases (MAPK), including extracellular signal-regulated kinase (ERK)1/2, as well

質問

1–2/2 質問  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 回答
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 回答
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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