GHRT-89HK

Human Ghrelin (TOTAL) RIA

• UNSPSCコード: 12161503
• eCl@ss: 32161000
• NACRES: NA.84

特性

• グレード: for protein analysis
• 品質水準: 100
• 詳細: ED₈₀ = 395 ± 88 pg/mL ED₅₀ = 895 ± 177 pg/mL ED₂₀ = 2015 ± 382 pg/mL ; analytes available: Ghrelin
• 特徴: accuracy 90–96%
• 化学種の反応性: human
• 感度測定範囲: 100-10000 pg/mL
• テクニック: radioimmunoassay: suitable
• UniProtアクセッション番号: Q9UBU3
• 検出方法: radioactive

詳細

詳細

FUNCTION: SwissProt: Q9UBU3 # Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility (By similarity).
SIZE: 117 amino acids; 12911 Da
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy.
PTM: O-octanoylation or O-decanoylation is essential for ghrelin activity. The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28- C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26. A small fraction of ghrelin, ghrelin-28- C10:1, may be modified with a singly unsaturated carboxylic acid. & Amidation of Leu-98 is essential for obestatin activity (By similarity).
SIMILARITY: SwissProt: Q9UBU3 ## Belongs to the motilin family.

アプリケーション

Two-day disequilibrium assay at 4°C. Sample volume: ≤ 100 μL Plasma (collected on ice) recommended

アナリシスノート

Linearity 99–146%

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• ピクトグラム: GHS02,GHS06,GHS09
• シグナルワード: Danger
• 危険有害性情報: H226,H302 + H332,H311,H319,H336,H411
• 注意書き: P210 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Flam. Liq. 3 - STOT SE 3
• ターゲットの組織: Central nervous system
• 保管分類コード: 3 - Flammable liquids