ABT253

Anti-Periostin Antibody (C-term)

1 mg/mL, from rabbit

• 別名: Periostin, PN, Osteoblast-specific factor 2, OSF-2
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 交差性: mouse
• 濃度: 1 mg/mL
• テクニック: western blot: suitable
• NCBIアクセッション番号: NP_001185694
• UniProtアクセッション番号: Q62009
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... POSTN(10631)

詳細

詳細

Periostin, also known as PN, or Osteoblast-specific factor 2 (OSF-2), and encoded by the gene POSTN/OSF2, is a secreted extracellular matrix protein that appears to be involved in inducing cell attachment and spreading as well as cell adhesion. In bone, Periostin enhances mineralization and assists in the incorporation of BMP1 protein into the fibronectin extracellular matrix of connective tissues. Periostin is preferentially expressed in periosteum and periodontal ligaments but can also be found expressed in developing heart and other tissues. Periostin is also over expressed in many cancers where is contributes to a growth-supportive role for such cancers and also aids in chemoresistance for cancers cells through the activation of the PI3K/Akt/surviving pathway.

特異性

This antibody detects a subset of splice variants of Periostin.

免疫原

A 188-amino acid bacterial fusion protein from the C-terminal region of mouse periostin.

Epitope: C-terminus

アプリケーション

Research Category
細胞骨格

Research Sub Category
接着分子（CAM）

Anti-Periostin Antibody (C-term) is an antibody against Periostin (C-term) for use in western blotting.

品質

Evaluated by Western Blotting in mouse lung tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Periostin in 10 µg of mouse lung tissue lysate.

ターゲットの説明

~80-85 kDa observed. Multiple splice variants detected.

物理的形状

Affinity purified

Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable