1.08219

トリズマ®塩酸塩

EMPROVE^® EXPERT

• 別名: トリズマ^® 塩酸塩 塩酸塩, TRIS HCl, TRIS 塩酸塩, トリス(ヒドロキシメチル)アミノメタン 塩酸塩, トロメタン塩酸塩
• 化学式: NH₂C(CH₂OH)₃ · HCl
• CAS番号: 1185-53-1
• 分子量: 157.60
• Beilstein: 3675235
• MDL番号: MFCD00012590
• UNSPSCコード: 12352107
• EC Index Number: 214-684-5

特性

• 蒸気圧: <1 Pa ( 50 °C)
• 品質水準: 500
• 製品種目: EMPROVE^® EXPERT
• 形状: solid
• 特徴: RNase and DNase free
• pH: 4.2 (20 °C, 100 g/L in H₂O)
• 有効pH範囲: 7.0-9.0
• pKa (25 °C): 8.1
• mp: 150.7 °C
• 溶解性: soluble 561 g/L
• 密度: 1.28 g/cm³ at 20.2 °C
• アプリケーション: parenterals
• 保管温度: 15-25°C
• SMILES記法: Cl.NC(CO)(CO)CO
• InChI: 1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H
• InChI Key: QKNYBSVHEMOAJP-UHFFFAOYSA-N

詳細

詳細

Finding the right chemical that matches your pharma and biopharma manufacturing needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for pharma and biopharma manufacturing withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Our SAFC^® portfolio of high-quality products for biopharmaceutical processing withstands strict quality control procedures and is produced according to MQ-500 requirements as defined by the M-Clarity program.

M-Clarity Program

As part of our EMPROVE^® Program, our raw materials are offered with EMPROVE^® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

その他情報

すべてのバッファーのpHは、温度や濃度に依存します。トリスバッファーの場合、温度が1°C低下するとpHは約0.03上昇し、希釈10倍ごとにpHは0.03～0.05低下します。精密なアプリケーションには、適切に校正した、ガラス／カロメル複合電極のpHメーターを使用してください。

Due to its low microbial and endotoxin limits, Tris(hydroxymethyl)aminomethane hydrochloride Emprove^® Expert is suitable for biopharma manufacturing needs.

法的情報

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable