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Merck

919012

Sigma-Aldrich

PEI Prime linear polyethylenimine

suitable for gene delivery

別名:

PEI

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100 MG
¥36,400

¥36,400

単価¥45,500割引20%

出荷予定日2025年3月30日


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100 MG
¥36,400

About This Item

化学式:
(C2H5N . HCl)n
CAS番号:
MDL番号:
UNSPSCコード:
12162002
NACRES:
NA.23

¥36,400

単価¥45,500割引20%

出荷予定日2025年3月30日


バルクの問い合わせ

品質水準

フォーム

powder

white to off-white

保管温度

2-8°C

SMILES記法

N(CCC)C

InChI

1S/C4H11N/c1-3-4-5-2/h5H,3-4H2,1-2H3

アプリケーション

PEI Prime is a cationic polymer designed for high-yield, reproducible and scalable drug and gene delivery. As a gene carrier, PEI forms a complex with nucleic acids via electrostatic self-assembly between the negatively charged nucleic acid phosphate groups and positively charged PEI amine groups. Due to this interaction, PEI has been extensively explored as a gene carrier and is one of the most effective synthetic polymers for the delivery of nucleic acids into cells through endocytosis.


PEI Prime uses an optimized form of PEI to reduce performance variance and speed process development time. Each batch of PEI Prime undergoes triplicate, quantitative performance testing using an SEAP reporter assay. PEI Prime is an excellent choice to produce any biologic cost-effectively, including recombinant proteins, antibodies, and viruses.

法的情報

PEI Prime is a trademark of Serochem LLC

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

919012-100MG:
919012-500MG:
919012-VAR:
919012-BULK:


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試験成績書(COA)

Lot/Batch Number

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文書ライブラリで、最近購入した製品の文書を検索できます。

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S M Zou et al.
The journal of gene medicine, 2(2), 128-134 (2000-05-16)
Several nonviral vectors including linear polyethylenimine (L-PEI) confer a pronounced lung tropism to plasmid DNA when injected into the mouse tail vein in a nonionic solution. and results We have optimized this route by injecting 50 microg DNA with excess
W T Godbey et al.
Biomaterials, 22(5), 471-480 (2001-02-24)
Poly(ethylenimine) (PEI) was used to transfect the endothelial cell line EA.hy 926, and the secreted levels of three gene products, tissue-type plasminogen activator (tPA), plasminogen activator inhibitor type 1 (PAI-1), and von Willebrand Factor (vWF), were assessed via ELISA. We
L Wightman et al.
The journal of gene medicine, 3(4), 362-372 (2001-09-01)
Efficient gene transfer is a major challenge for non-viral gene therapy. Understanding how non-viral vectors initiate gene expression could lead to the development of new future vectors with enhanced efficacy. Linear or branched polyethylenimine (PEI)/DNA complexes were generated in varying

質問

1–3/3 質問  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 回答
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 回答
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. What is the Degree Polimerization?

    1 回答
    1. The degree of polymerization has not been determined for this product.

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レビュー

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