900864

4-(Bromomethyl)-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• 別名: Bromo sulfonyl fluoride TMS-alkyne, Probe building block
• 実験式（ヒル表記法）: C₁₂H₁₄BrFO₂SSi
• CAS番号: 2088828-99-1
• 分子量: 349.29
• UNSPSCコード: 12352200
• NACRES: NA.22

特性

• 品質水準: 100
• アッセイ: ≥95%
• 形状: powder or crystals
• 利用可能性: available only in USA
• 保管温度: −20°C
• SMILES記法: O=S(C(C(C#C[Si](C)(C)C)=C1)=CC=C1CBr)(F)=O

詳細

アプリケーション

Used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

その他情報

• 1.Technology Spotlight: Trifunctional Probe Building Blocks
• 2.Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

安全性情報

• ピクトグラム: GHS02
• シグナルワード: Danger
• 危険有害性情報: H242
• 注意書き: P210 - P234 - P235 - P240 - P370 + P378 - P403
• 危険有害性の分類: Self-react. C
• 保管分類コード: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable