(R)-(+)-プロピレンオキシドは、キラル化合物の合成におけるキラル構成要素または中間体として一般的に使用されます。例えば、キラル触媒の存在下でCO2と反応させることで環状プロピレンカーボネートを合成するために使用できます。β-ガラクトシダーゼの in vivo検出に使用できる磁気共鳴 (MR) 造影剤の調製の出発物質としても使用されます。
Journal of molecular medicine (Berlin, Germany), 98(11), 1639-1656 (2020-09-24)
Fibulin-3 (F3) is an extracellular matrix glycoprotein found in basement membranes across the body. An autosomal dominant R345W mutation in F3 causes a macular dystrophy resembling dry age-related macular degeneration (AMD), whereas genetic removal of wild-type (WT) F3 protects mice
Activation of type 1 cannabinoid (CB1) receptors by endogenous, exogenous (cannabis derivatives) or synthetic cannabinoids (i.e., CP 55.940, Win-2) has a wide variety of behavioral effects due to the presence of CB1 receptors in the brain. In situ hybridization and
Particulate methane monooxygenase (pMMO) is a membrane-bound metalloenzyme that oxidizes methane to methanol in methanotrophic bacteria. The nature of the pMMO active site and the overall metal content are controversial, with spectroscopic and crystallographic data suggesting the presence of a