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Merck

CHRNA3

cholinergic receptor, nicotinic, alpha 3 (neuronal)

別名:
LNCR2, NACHRA3, PAOD2
Species:
UniProtKB ID:
遺伝子ID:
  • Human(1136) Summary: This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
  • Mouse(110834) cholinergic receptor, nicotinic, alpha polypeptide 3
  • Rat(25101) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • domestic guinea pig(100730977) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • naked mole-rat(101701279) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • sheep(101123239) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • Domestic Rabbit(100342666) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • dog(482111) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • cow(282702) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • domestic cat(100037403) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • Zebrafish(568467) cholinergic receptor, nicotinic, alpha 3
  • chicken(386578) cholinergic receptor, nicotinic, alpha 3

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Small Molecule - Agonist

製品番号
詳細
Species
(±)-ニコチン, ≥99% (TLC), liquid,
Species
human, rat
塩化カルバモイルコリン, ≥98% (titration), crystalline,
Species
human, mouse, rat
トロピセトロン 一塩酸塩, solid, ≥98% (HPLC),
Species
rat, human
(−)-ニコチン 溶液, 1.0 mg/mL, analytical standard, for drug analysis,
Species
human, mouse, rat
(−)-ニコチン, ≥99% (GC), liquid,
Species
human, mouse, rat

Small Molecule - Antagonist

製品番号
詳細
Species
シチシン, ≥99%, powder,
Species
rat
(±)-ニコチン, ≥99% (TLC), liquid,
Species
human, rat
塩化カルバモイルコリン, ≥98% (titration), crystalline,
Species
human, mouse, rat
メカミラミン 塩酸塩, ,
Species
human
トロピセトロン 一塩酸塩, solid, ≥98% (HPLC),
Species
rat, human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-CHRNA3 antibody produced in rabbit, affinity isolated antibody,
交差性
dog, human, rabbit
アプリケーション
western blot
単クローン性抗ニコチン性アセチルコリン受容体(α1、α3、α5サブユニット) ラット宿主抗体, clone mAb 35, purified immunoglobulin, buffered aqueous solution,
交差性
chicken, eel, human
アプリケーション
immunohistochemistry

Small Molecule - Blocker

製品番号
詳細
Species
テトラエチルアンモニウムクロリド, ≥98% (titration),
Species
human
臭化ヘキサメトニウム, ,
Species
human
塩化ヘキサメトニウム, solid (hygroscopic),
Species
human
キヌレン酸, ≥98%,
Species
rat, human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human CHRNA3,
Species
human
MISSION® esiRNA, targeting mouse Chrna3,
Species
mouse