53353-U

Ascentis^® Express 90 Å Phenyl-Hexyl (2.7 μm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

• Sinonimo/i: Core-shell (SPP) Fused Core Phenyl HPLC column
• Codice UNSPSC: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

Proprietà

• product name: Ascentis^® Express Phenyl-Hexyl, 2.7 μm HPLC Column, 2.7 μm particle size, L × I.D. 15 cm × 4.6 mm
• Materiali: stainless steel column
• agenzia: suitable for USP L11
• Nome Commerciale: Ascentis^®
• Caratteristiche: endcapped
• Produttore/marchio commerciale: Ascentis^®
• Confezionamento: 1 ea of
• Parametri: 60 °C temp. range; 600 bar max. pressure (9000 psi)
• tecniche: HPLC: suitable; LC/MS: suitable; UHPLC-MS: suitable; UHPLC: suitable
• Lungh. × D.I.: 15 cm × 4.6 mm
• Area superficiale: 135 m²/g
• Impurezze: <5 ppm metals
• Matrice: Fused-Core particle platform; superficially porous particle
• Gruppo funzionale matrice: phenylhexyl phase
• Dimensione particelle: 2.7 μm
• Dimensione pori: 90 Å
• Intervallo di pH: 2-9
• applicazioni: food and beverages
• Tecnica di separazione: reversed phase

Descrizione

Descrizione generale

The Phenyl-Hexyl phase has unique selectivity arising from solute interaction with the aromatic ring and its delocalized electrons. It is complementary (orthogonal) to both C18 and RP-Amide phases because of this unique aromaticity. The Phenyl-Hexyl phase also tend to exhibit good shape selectivity, which may originate from solute multipoint interaction with the planar ring system. More retention and selectivity will often be observed for solutes with aromatic electron-withdrawing groups (fluorine, nitro, etc.) or with a delocalized heterocyclic ring system such as the benzodiazepine compounds.

Applicazioni

• A Different Perspective on the Characterization of a New Degradation Product of Flibanserin With HPLC-DAD-ESI-IT-TOF-MSn and Its Pharmaceutical Formulation Analysis With Inter-Laboratory Comparison.: This study utilizes the Ascentis^® Express Phenyl-Hexyl, 2.7 μm HPLC column to characterize degradation products of flibanserin, demonstrating its efficacy in high-resolution analytical applications (Geven et al., 2023).
• HPLC with spectrophotometric or mass spectrometric detection for quantifying very-long chain fatty acids in human plasma and its association with cardiac risk factors.: The Ascentis^® Express Phenyl-Hexyl column was employed for precise quantification of fatty acids, linking its use to critical clinical research on cardiac risk factors (Shrestha et al., 2021).
• A fully automated and fast method using direct sample injection combined with fused-core column on-line SPE-HPLC for determination of ochratoxin A and citrinin in lager beers.: This research highlights the efficiency of the Ascentis^® Express Phenyl-Hexyl column in detecting contaminants in beverages, emphasizing its role in food safety analysis (Lhotska et al., 2016).
• A study of retention characteristics and quality control of nutraceuticals containing resveratrol and polydatin using fused-core column chromatography.: This study explores the retention characteristics of nutraceuticals using the Ascentis^® Express Phenyl-Hexyl column, showcasing its utility in quality control of health supplements (Fibigr et al., 2016).
• An on-line SPE-HPLC method for effective sample preconcentration and determination of fenoxycarb and cis, trans-permethrin in surface waters.: The Ascentis^® Express Phenyl-Hexyl column was integral in preconcentrating and analyzing pesticide residues in environmental samples, underscoring its environmental analytical applications (Satinsky et al., 2015).

Note legali

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable