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N0786

Sigma-Aldrich

β-Nicotinamide adenine dinucleotide, reduced disodium salt

~98%, pkg of 1 mg (per vial)

Sinonimo/i:

β-DPNH, β-NADH, Coenzyme I reduced disodium salt, Diphosphopyridine nucleotide reduced disodium salt

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About This Item

Formula empirica (notazione di Hill):
C21H27N7Na2O14P2
Numero CAS:
Peso molecolare:
709.40
Beilstein:
5230241
Numero CE:
Numero MDL:
Codice UNSPSC:
41106305
ID PubChem:
NACRES:
NA.51

Saggio

~98%

Livello qualitativo

Forma fisica

powder

Confezionamento

pkg of 1 mg (per vial)

Solubilità

10 mM NaOH: 0.1 mg/mL, clear, colorless

Stringa SMILE

[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@H](O)[C@@H]2O

InChI

1S/C21H29N7O14P2.2Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33;;/h1,3-4,7-8,10-11,13-16,20-21,29-32H,2,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25);;/q;2*+1/p-2/t10-,11+,13-,14+,15-,16+,20-,21+;;/m0../s1
QRGNQKGQENGQSE-QUWMEQBESA-L

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Categorie correlate

Applicazioni

β-Nicotinamide adenine dinucleotide, reduced disodium salt has been used in the preparation of standard curve.

Azioni biochim/fisiol

β-Nicotinamide adenine dinucleotide (β-NADH) reduced form is an essential cofactor in all the living organisms. β-NADH functions as a hydride donor in biochemical redox reactions.
Electron donor

Ricostituzione

Solutions should be prepared fresh and used promptly.

Altre note

Packaged based on NADH content as determined by UV-Vis.
This is the common form of NADH; do not confuse with α-NADH.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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Milk composition and health status from mammary gland quarters adjacent to glands affected with naturally occurring clinical mastitis
Paixao MG, et al.
Journal of Dairy Science, 100(9), 7522-7533 (2017)
The biosynthesis of nicotinamide adenine dinucleotides in bacteria
Begley TP, et al.
Vitamins and Hormones, 61, 103-119 (2001)
Richard P Ebstein et al.
FEBS letters, 585(11), 1529-1536 (2011-05-12)
Increasing evidence suggests that the nonapeptide, oxytocin (OT), helps shape social and affiliative behaviors not only in lower mammals but also in humans. Recently, an essential mediator of brain OT release has been discovered, ADP-ribosyl cyclase and/or CD38. We have
Weihai Ying
Frontiers in bioscience : a journal and virtual library, 11, 3129-3148 (2006-05-25)
Increasing evidence has indicated that NAD+ and NADH play critical roles not only in energy metabolism, but also in cell death and various cellular functions including regulation of calcium homeostasis and gene expression. It has also been indicated that NAD+
Xiaoling Li et al.
International journal of biological sciences, 7(5), 575-587 (2011-05-27)
Sirtuins are highly conserved NAD+-dependent protein deacetylases and/or ADP-ribosyltransferases that can extend the lifespan of several lower model organisms including yeast, worms and flies. The seven mammalian sirtuins, SIRT1 to SIRT7, have emerged as key metabolic sensors that directly link

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