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MHS128

Sigma-Aldrich

Mayer′s Hematoxylin Solution

Sinonimo/i:

(6aS,11bR)-7,11b-Dihydroindeno[2,1-c]chromene-3,4,6a,9,10(6H)-pentol, Delafield′s hematoxylin, Progressive stains

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4 L
267,00 €

267,00 €


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4 L
267,00 €

About This Item

Numero MDL:
Codice UNSPSC:
41116124
ID PubChem:
NACRES:
NA.47

267,00 €


Per informazioni sulla disponibilità, contatta il Servizio Clienti.

Richiedi un ordine bulk

Stato

solution

Livello qualitativo

Durata

Expiry date on the label.

IVD

for in vitro diagnostic use

Concentrazione

1 g/L

pH

2.4 (25 °C)

applicazioni

hematology
histology

Temperatura di conservazione

room temp

Stringa SMILE

Oc1cc2C[C@@]3(O)COc4c(O)c(O)ccc4[C@H]3c2cc1O

InChI

1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1
WZUVPPKBWHMQCE-XJKSGUPXSA-N

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Descrizione generale

Used as a counterstain for procedures such as immunohistochemistry or laser microdissection.

Applicazioni

General purpose nuclear stain, progressive type. Used with hematoxylin and eosin staining.

Altre note

1 g/L certified hematoxylin

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Shun-Jie Chen et al.
Oncology reports, 37(2), 1148-1158 (2016-12-14)
Acute kidney injury (AKI) is a disease where kidney function is lost almost instantaneously; it can develop very rapidly over few hours to maximum of few days. Despite the advent of technology, the clinical management against this disease is very
Stephany Orjuela et al.
BMC cancer, 20(1), 290-290 (2020-04-08)
Identifying molecular differences between primary and metastatic colorectal cancers-now possible with the aid of omics technologies-can improve our understanding of the biological mechanisms of cancer progression and facilitate the discovery of novel treatments for late-stage cancer. We compared the DNA
Adam Smith et al.
Molecular cancer therapeutics, 8(6), 1666-1675 (2009-06-11)
Although viridins like wortmannin (Wm) have long been examined as anticancer agents, their ability to self-activate has only recently been recognized. Here, we describe the cytostatic effects of a self-activating viridin (SAV), which is an inactive, polymeric prodrug. SAV self-activates
Hideki Ishii et al.
Bioorganic & medicinal chemistry letters, 22(3), 1469-1474 (2012-01-17)
SAR studies for the exploration a novel class of anti-human immunodeficiency virus type 1 (HIV-1) agents based on the hematoxylin structure (1) are described. The systematic deoxygenations of 1 including asymmetric synthesis were conducted to obtain a compound showing high
J Jason Hoth et al.
Shock (Augusta, Ga.), 31(4), 376-381 (2008-07-31)
Blunt chest trauma resulting in pulmonary contusion with an accompanying acute inflammatory response is a common but poorly understood injury. We previously demonstrated that toll-like receptor 2 (TLR-2) participates in the inflammatory response to lung injury. We hypothesized that the

Domande

1–6 di 6 domande  
  1. What is the Department of Transportation shipping information for this product?

    1 risposta
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Utile?

  2. There are several Mayer's Hematoxylins listed on the website, beginning with the letters MHS.  What are the differences?

    1 risposta
    1. Products MHS1, MHS16, MHS32, MHS80 and MHS128 are in fact the same product. In this case a unique product number was assigned to each package size. Other than the package size, there are no differences in formulation or use.

      Utile?

  3. There is also a product listed on the website as Hematoxylin Solution According to Mayer. What is the difference between product 51275 and the various Mayer's Hematoxylin solutions?

    1 risposta
    1. The basic formulations are the same. Both include chloral hydrate, although some of the concentrations could vary slightly. Product 51275 is not intended for In Vitro Diagnostic Use. Product 51275 is not CE Marked. The various Mayer's Hematoyxlin solutions are intended For In Vitro Diagnostic Use and are also CE Marked. Product inserts are available for various languages.

      Utile?

  4. The slides were stained with Mayer's Hematoxylin but the nuclei are not blue. Why?

    1 risposta
    1. The nuclei will originally appear as the same color as the solution. Only after the slides have been "blued" will the nuclei appear blue. The pH of the solution is acidic. This acidic pH promotes specific staining. However the slides must be washed in an neutral or alkaline solution for the color to shift to blue. Prolonged warm water washes in tap water are often sufficient for the bluing to occur. To shorten the time spent in washing, various bluing agents are often used to shorten the blueing process. Scott's Tap Water Substitute (Product No. S5134) is one such blueing agent.

      Utile?

  5. The website states that Mayer's Hematoxylin solution is a progressive type hematoxylin. What is a progressive type hematoxylin?

    1 risposta
    1. Hematoxylin solutions are generally classified as either progressive or regressive. Progressive formulations will stain only the nucleus. No staining should occur within the cytoplasm. Regressive hematoxylins have higher dye contents and if used for sufficient periods of time will overstain both the nucleus and the cytoplasm. Acid differentiation is required to remove the excessive stain from the cytoplasm and nucleus. This differentiation take practice to master. Too much or too little stain can be removed during differentiation, resulting in poorly stained slides. For users lacking extensive experience with the Hematoxylin and Eosin staining procedure,  progressive hematoxylin formulations are often the better choice.

      Utile?

  6. Is chloral hydrate used in the preparation of Mayer's Hematoxylin?  Does this mean the solution is controlled as a DEA Schedule IV product?

    1 risposta
    1. Yes, chloral hydrate is included in the formulation. No, the solution is not controlled as a DEA Schedule IV product. Once the choral hydrate is mixed with the remaining chemicals, it is impossible to obtain the chloral hydrate in a purified form.

      Utile?

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