L′adenosina 5′ trifosfato (ATP) è un componente fondamentale dell′accumulo di energia e del metabolismo in vivo. L′ATP si usa in molti processi cellulari: respirazione, reazioni di biosintesi, motilità e divisione cellulare. L′ATP è un substrato di molte chinasi coinvolte nella trasmissione dei segnali cellulari e delle adenilciclasi che producono il secondo messaggero cAMP. L′ATP fornisce l′energia metabolica per azionare le pompe metaboliche. L′ATP agisce da coenzima in un′ampia gamma di reazioni enzimatiche.
Azioni biochim/fisiol
Agonista dei purinocettori P2.
Agonista purinergico P2; aumenta l′attività dei canali K+ attivati da Ca2+; substrato per i sistemi enzimatici ATP-dipendenti
Langmuir : the ACS journal of surfaces and colloids, 25(3), 1582-1587 (2009-01-28)
Cellulase is an enzymatic complex which synergically promotes the degradation of cellulose to glucose. The adsorption behavior of cellulase from Trichoderma reesei onto Si wafers or amino-terminated surfaces was investigated by means of ellipsometry and atomic force microscopy (AFM) as
The inflammasome machinery has recently been recognized as an emerging pillar of innate immunity. However, little is known regarding the interaction between the classical interferon (IFN) response and inflammasome activation in response to norovirus infection. We found that murine norovirus
Throughout the last several decades, vaccination has been key to prevent and eradicate infectious diseases. However, many pathogens (e.g., respiratory syncytial virus [RSV], influenza, dengue, and others) have resisted vaccine development efforts, largely because of the failure to induce potent
The AAA+ protein disaggregase, Hsp104, increases fitness under stress by reversing stress-induced protein aggregation. Natural Hsp104 variants might exist with enhanced, selective activity against neurodegenerative disease substrates. However, natural Hsp104 variation remains largely unexplored. Here, we screened a cross-kingdom collection
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(6), 2747-2765 (2015-02-13)
It is unknown whether neurons can dynamically control the capacity for secretion by promptly changing the number of plasma membrane voltage-gated Ca(2+) channels. To address this, we studied peptide release from the bag cell neurons of Aplysia californica, which initiate
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