Iron oxide nanoparticles are magnetic single crystals and can be used as magnetic resonance imaging contrast reagents for in-vivo imaging , drug delivery vehicle, hyperthermia genertor for therapy, adjuvant for vaccine, and magnetic sensing probe for in-vitro diagnostics. Ocean NanoTech′s carboxyl terminated iron oxide nanocrystals of various diameters (10 nm-30 nm) are now available in an easy-to-use kit format to enable researchers to conjugate proteins/ligands of their own choice to these iron oxide nanoparticles. The kit contains sufficient reagents & components for performing at least 5 conjugation reactions using 1mg iron oxide nanoparticles per reaction. The iron oxide nanoparticles are activated using carbodiimide and N-hydroxysuccinimide followed by conjugation to amino groups that are present on the target protein/ligand such as bovine serum albumin, streptavidin and immunoglobulin.
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