![1-[3-(Dimethylamino)propyl]-3-ethylcarbodiimide methiodide](/deepweb/assets/sigmaaldrich/product/structures/414/134/4eb9c126-d7f9-4e12-9e3a-95cb077824fd/640/4eb9c126-d7f9-4e12-9e3a-95cb077824fd.png)
Unfortunately, cell toxicity is not a specification tested for this product.
130672
N-Hydroxysuccinimide
N-Hydroxysuccinimide
98%
Sinonimo/i:
1-Hydroxy-2,5-pyrrolidinedione, HOSu, NHS
Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Scegli un formato
5 G
24,00 €
25 G
41,40 €
100 G
135,00 €
250 G
315,00 €
1 KG
699,00 €
Scegli un formato
Cambia visualizzazione
5 G
24,00 €
25 G
41,40 €
100 G
135,00 €
250 G
315,00 €
1 KG
699,00 €
About This Item
Formula empirica (notazione di Hill):
C4H5NO3
Numero CAS:
Peso molecolare:
115.09
Beilstein:
113913
Numero CE:
Numero MDL:
Codice UNSPSC:
12352115
ID PubChem:
NACRES:
NA.22
Prodotti consigliati
Saggio
98%
Stato
solid
Punto di fusione
95-98 °C (lit.)
Gruppo funzionale
imide
Stringa SMILE
ON1C(=O)CCC1=O
InChI
1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2
NQTADLQHYWFPDB-UHFFFAOYSA-N
Cerchi prodotti simili? Visita Guida al confronto tra prodotti
Applicazioni
N-Hydroxysuccinimide can be used in the synthesis of N-hydroxysuccinimide ester via dehydration reaction in the presence of dicyclohexylcarbodiimide in carboxylic acid.[1]
N-Hydroxysuccinimide has been used in the synthesis of intermediates such as:
It has also been used in a protocol for the surface modification of microchannels of a microfluidic-integrated surface plasmon resonance (SPR) platform for the detection and quantification of bacterial pathogens.[5]
- N
- -succinimidyl 3-(di-tert-butylfluorosilyl)benzoate[2]
- 4-[2,2-bis[(p-tolylsulfonyl)-methyl] acetyl]benzoic acid-NHS ester[3]
- N-succinimidyl 3-iodobenzoate[4]
It has also been used in a protocol for the surface modification of microchannels of a microfluidic-integrated surface plasmon resonance (SPR) platform for the detection and quantification of bacterial pathogens.[5]
Avvertenze
Danger
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Eye Dam. 1 - Skin Irrit. 2
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
Scegli una delle versioni più recenti:
Certificati d'analisi (COA)
Lot/Batch Number
Non trovi la versione di tuo interesse?
Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.
Possiedi già questo prodotto?
I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
I clienti hanno visto anche
Polycyclic Aromat. Compd., 3, 781-781 (1993)
PEGylation of native disulfide bonds in proteins.
Brocchini S
Nature Protocols, 1(5), 2241-2241 (2006)
Zbigniew Czajgucki et al.
Journal of peptide science : an official publication of the European Peptide Society, 12(10), 653-662 (2006-07-19)
Edeines are pentapeptide amide antibiotics composed of four nonprotein amino acids, glycine, and polyamine. They exhibit antimicrobial and immunosuppressive activities and are universal inhibitors of translation. Moreover, it was proven that the free ionizable carboxy group in the (2R, 6S
Preparation of N-succinimidyl 3-[* I] iodobenzoate: an agent for the indirect radioiodination of proteins.
Vaidyanathan G
Nature Protocols, 1(2), 707-707 (2006)
Cong Li et al.
Journal of the American Chemical Society, 128(47), 15072-15073 (2006-11-23)
The conjugate of bacterial cytosine deaminase (bCD) and poly-l-lysine (PLL) that was functionalized with biotin, rhodamine, and Gd3+-DOTA was synthesized and characterized. It demonstrated high relaxivity, improved enzymatic specificity to prodrug 5-fluorocytosine, low cytotoxicity, efficient cell uptake, and high enzymatic
Articoli
Explore methods for molecular monolayers on silicon surfaces, their properties, and applications in molecular electronics and sensing.
Professor Aran discusses engineering graphene-based materials through careful functionalization, enabling diverse applications.
-
is there any reported data for cell's toxicity for this compound?
1 risposta-
Utile?
-
-
How can I determine the shelf life / expiration / retest date of this product?
1 risposta-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdfUtile?
-
-
How is shipping temperature determined? And how is it related to the product storage temperature?
1 risposta-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
Utile?
-
-
What is the storage temperature of NHS? (Product number: 130672)
1 risposta-
This product is stored at room temperature.
Utile?
-
-
Hello, Could you tell me the percentage of impurities and define specifically which impurities we can find in this reagent ? Thank you,
1 risposta-
The impurities of this product are not identified or quantified.
Please view the Specification Sheet to see the specified tests: https://www.sigmaaldrich.com/specification-sheets/190/101/130672-BULK_______ALDRICH__.pdf.Utile?
-
-
Does N-Hydroxysuccinimide WATER SOLUBLE?
1 risposta-
Yes, this product is water soluble at 50mg/ml
Utile?
-
-
What is the purity of Product 130672, N-Hydroxysuccinimide?
1 risposta-
The purity is lot specific and will be stated on the Specification Sheet.
Utile?
-
-
Does N-Hydroxysuccinimide go by any other names?
1 risposta-
Yes, N-Hydroxysuccinimide is also referred to by the acronym NHS and is also referred to by the synonyms 1-Hydroxy-2,5-pyrrolidinedione and HOSu.
Utile?
-
-
What is the solution stability of Product 130672, N-Hydroxysuccinimide?
1 risposta-
Sigma-Aldrich does not evaluate 130672 for solution stability. Therefore, it is advisable to prepare a solution fresh for each use. Please note, the product is moisture sensitive.
Utile?
-
-
What is the Department of Transportation shipping information for this product?
1 risposta-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Utile?
-
Filtri attivi
Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
Contatta l'Assistenza Tecnica.
