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Merck

CHRM3

cholinergic receptor, muscarinic 3

Sinonimi:
EGBRS, HM3
Specie:
Human CHRM3 (1131), Mouse Chrm3 (12671), Rat Chrm3 (24260), Domestic Rabbit CHRM3 (100355313), sheep CHRM3 (443189), domestic cat CHRM3 (101100919), cow CHRM3 (281685), Horse CHRM3 (100056633), dog CHRM3 (403827), domestic guinea pig Chrm3 (100379235)
ID UniProtKB:
P20309, Q0VAJ8, Q4QRI3, Q5VXY2, Q9HB60
ID gene:
  • Human(1131) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. [provided by RefSeq, Jul 2008]
  • Mouse(12671) cholinergic receptor, muscarinic 3, cardiac
  • Rat(24260) cholinergic receptor, muscarinic 3
  • Domestic Rabbit(100355313) cholinergic receptor, muscarinic 3
  • sheep(443189) cholinergic receptor, muscarinic 3
  • domestic cat(101100919) cholinergic receptor, muscarinic 3
  • cow(281685) cholinergic receptor, muscarinic 3
  • Horse(100056633) cholinergic receptor, muscarinic 3
  • dog(403827) cholinergic receptor, muscarinic 3
  • domestic guinea pig(100379235) cholinergic receptor, muscarinic 3, cardiac
  • chicken(396364) cholinergic receptor, muscarinic 3

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Small Molecule - Agonist

Numero di prodotto
Descrizione
Specie
A6625
Cloruro di acetilcolina, ≥99% (TLC),
Specie
human
A2661
Cloruro di acetilcolina, suitable for cell culture,
Specie
human
A7000
Acetylcholine iodide, ≥97%,
Specie
human
A9101
Cloruro di acetilcolina, pkg of 150 mg (per vial),
Specie
human
PHR1511
Carbachol, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human

Small Molecule - Antagonist

Numero di prodotto
Descrizione
Specie
1347507
Ipratropium bromide, United States Pharmacopeia (USP) Reference Standard,
Specie
human
1699005
Tropicamide, United States Pharmacopeia (USP) Reference Standard,
Specie
human
1156000
Cyclopentolate hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human
I0360000
Ipratropium bromide, European Pharmacopoeia (EP) Reference Standard,
Specie
human
C3245000
Cyclopentolate hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
AB9018
Anti-Muscarinic Acetylcholine Receptor m3 Antibody, Chemicon®, from rabbit,
Reattività con
rat
Applicazione
western blot
HPA024106
Anti-CHRM3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
SAB5700750
Anti-CHRM3 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
western blot
M0194
Anti-Muscarinic Acetylcholine Receptor (M3) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reattività con
human, mouse, rat
Applicazione
western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
A8404
Amitriptyline hydrochloride, ≥98% (TLC), powder,
Specie
human
D4526
Doxepin hydrochloride, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
Specie
human
51330
Harmaline, ≥95%,
Specie
human, rat

Small Molecule - Ligand

Numero di prodotto
Descrizione
Specie
A138
Aminobenztropine, solid,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
EHU027151
MISSION® esiRNA, targeting human CHRM3,
Specie
human