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V4015

Sigma-Aldrich

Verbascoside

≥99% (HPLC)

Szinonimák:

Acetoside, Kusaginin

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About This Item

Tapasztalati képlet (Hill-képlet):
C29H36O15
CAS-szám:
61276-17-3
Molekulatömeg:
624.59
MDL-szám:
MFCD00221751
UNSPSC kód:
12352200
PubChem Substance ID:
329829047
NACRES:
NA.25

Minőségi szint

200

Teszt

≥99% (HPLC)

alkalmazás(ok)

metabolomics
vitamins, nutraceuticals, and natural products

tárolási hőmérséklet

room temp

SMILES string

C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO)[C@H]2OC(=O)\C=C\c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O

InChI

1S/C29H36O15/c1-13-22(36)23(37)24(38)29(41-13)44-27-25(39)28(40-9-8-15-3-6-17(32)19(34)11-15)42-20(12-30)26(27)43-21(35)7-4-14-2-5-16(31)18(33)10-14/h2-7,10-11,13,20,22-34,36-39H,8-9,12H2,1H3/b7-4+/t13-,20+,22-,23+,24+,25+,26+,27+,28+,29-/m0/s1

Nemzetközi kémiai azonosító kulcs

FBSKJMQYURKNSU-ZLSOWSIRSA-N

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Általános leírás

Verbascoside, also known as acteoside, is a hydrophilic plant compound first isolated from mullein (Verbascum sinuatum L.). The chemical structure of verbascoside comprises hydroxyphenylethyl and cinnamic acid moieties bound to a β-glucopyranose via a glycosidic bond.

Alkalmazás

Verbascoside has been used:
  • as a reference standard for high-performance liquid chromatography (HPLC) analysis
  • as a reference standard for detection of phenolic compounds in olive mill wastewater and pomace by high-performance liquid chromatography (HPLC)-diode-array detector (DAD)-qTOF system
  • to test its anti-viral activity against respiratory syncytial virus (RSV) in HEP2 cells and A549 cells

Biokémiai/fiziológiai hatások

Verbascoside has anti-inflammatory and photoprotective properties. It has shown neuroprotective effects on PC12 neuronal cells against neurotoxicity. Verbascoside is proven to be a potent inhibitor of xanthine oxidase (XOD) in in vitro studies.
Phenylethanoid glycoside. Antioxidant and antiproliferative.

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Válasszon a legfrissebb verziók közül:

Analitikai tanúsítványok (COA)

Lot/Batch Number
SLCP4923
SLCQ1161
SLCP8197
SLCP7825
SLCD6521

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Aucubin analytical standard

Supelco

55561

Aucubin

Oleuropein ≥98.0%

Sigma-Aldrich

12247

Oleuropein

Harpagide phyproof® Reference Substance

PHL89703

Harpagide

Forsythoside A phyproof® Reference Substance

PHL80310

Forsythoside A

Aucubin primary reference standard

00090590

Aucubin

Oleuropein European Pharmacopoeia (EP) Reference Standard

Y0000805

Oleuropein

3-Hydroxytyrosol ≥98% (HPLC)

Sigma-Aldrich

H4291

3-Hydroxytyrosol

Oleuropein analytical standard

Supelco

92167

Oleuropein

Luteolin-7-O-β-D-glucuronide primary reference standard

04480585

Luteolin-7-O-β-D-glucuronide

Guo-Qing Sheng et al.
European journal of pharmacology, 451(2), 119-124 (2002-09-17)
The neuroprotective effects of verbascoside, one of phenylpropanoid glucoside isolated from the Chinese herbal medicine Buddleja officinalis Maxim, on 1-methyl-4-phenylpyridinium ion (MPP(+)) induced apoptosis and oxidative stress in PC12 neuronal cells were investigated. Treatment of PC12 cells with MPP(+) for
Kalina Alipieva et al.
Biotechnology advances, 32(6), 1065-1076 (2014-07-23)
Phenylethanoid glycosides are naturally occurring water-soluble compounds with remarkable biological properties that are widely distributed in the plant kingdom. Verbascoside is a phenylethanoid glycoside that was first isolated from mullein but is also found in several other plant species. It
Yin Wan et al.
International journal of biological macromolecules, 93(Pt A), 609-614 (2016-11-05)
In this study, we analyzed the inhibitory effect of verbascoside against xanthine oxidase (XOD) in vitro by using animal model and in vivo by direct inhibition assay. Results showed that verbascoside could reduce uric acid in rat serum and inhibit
Tae Won Jang et al.
Molecular medicine reports, 22(3), 2076-2084 (2020-06-26)
Abeliophyllum distichum Nakai is a Korean endemic plant of the Oleaceae family that contains acteoside, a glycosylated caffeic acid, with neuroprotective, anti‑inflammatory and antibacterial properties. Previous studies, involving Accelerated Chromatographic Isolation, a high‑performance liquid chromatography‑photodiode array detector and a liquid
Kiramage Chathuranga et al.
Viruses, 11(7) (2019-07-07)
The herbs Plantago asiatica and Clerodendrum trichotomum have been commonly used for centuries in indigenous and folk medicine in tropical and subtropical regions of the world. In this study, we show that extracts from these herbs have antiviral effects against
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