SMB01061

Emetine

≥90% (LC/MS-ELSD)

• Szinonimák: (-)-Emetine
• Tapasztalati képlet (Hill-képlet): C₂₉H₄₀N₂O₄
• CAS-szám: 483-18-1
• Molekulatömeg: 480.64
• MDL-szám: MFCD00242944
• UNSPSC kód: 12352205
• NACRES: NA.25

Tulajdonságok

• biológiai forrás: plant
• Teszt: ≥90% (LC/MS-ELSD)
• Forma: solid
• molekulatömeg: 480.64
• oldhatóság: water: soluble
• alkalmazás(ok): metabolomics; vitamins, nutraceuticals, and natural products
• tárolási hőmérséklet: −20°C
• SMILES string: N21[C@@H](C[C@@H]([C@H](C2)CC)C[C@H]4NCCc5c4cc(c(c5)OC)OC)c3c(cc(c(c3)OC)OC)CC1
• InChI: 1S/C29H40N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h13-16,18,21,24-25,30H,6-12,17H2,1-5H3/t18-,21-,24+,25-/m0/s1
• Nemzetközi kémiai azonosító kulcs: AUVVAXYIELKVAI-CKBKHPSWSA-N

Leírás

Általános leírás

Emetine, a pyridoisoquinoline alkaloid, is a bioactive natural compound commonly derived from plants such as Helichrysum revolutum, Sphaerophysa salsula, Coryphantha elephantidens, Uragoga ipecacuanha, Uragoga acuminata and Clonostachys rosea. Current research suggests that this metabolite acts as an inhibitor and may exhibit diverse biological activities, including antiprotozoal, antitumor, anti-inflammatory, anti-infective, antimalarial, and antiviral properties.

Alkalmazás

Emetine is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and drug discovery research.

Biokémiai/fiziológiai hatások

Emetine is the principal pyridoisoquinoline of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae.

Emetine is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in eukaryotic cells but not prokaryotic cells.

Tulajdonságok és előnyök

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Egyéb megjegyzések

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Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable