Ugrás a tartalomra
Merck

SMB00801

Lipopolysaccharides from Proteus vulgaris

purified by phenol extraction

Szinonimák:

LPS

Bejelentkezés a Szervezeti és Szerződéses árazás megtekintéséhez

Méret kiválasztása

25 MG

100 000,00 Ft

100 000,00 Ft


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Erről a tételről

UNSPSC kód:
12352211
NACRES:
NA.28

Ugrás ide:

Műszaki ügyfélszolgálat
Segítségre van szüksége? Szakértő tudósaink csapata készséggel áll az Ön rendelkezésére.
Segíthetünk?

biológiai forrás

bacterial (Proteus vulgaris)

Minőségi szint

Forma

lyophilized powder

tisztítva

phenol extraction

szennyeződések

≤3% Protein (Lowry)

szín

white to yellow cast

oldhatóság

water: 4.90-5.10 mg/mL, faintly hazy to hazy, colorless to faintly yellow

kiszállítva

ambient

tárolási hőmérséklet

2-8°C

Hasonló termékek összehasonlítása

Teljes összehasonlítás megtekintése

Különbségek megjelenítése

1 of 4

Ez a tétel
SMB00704L6261L2630
biological source

bacterial (Proteus vulgaris)

biological source

bacterial (Proteus mirabilis)

biological source

Salmonella enterica (serotype minnesota)

biological source

Escherichia coli (O111:B4)

solubility

water: 4.90-5.10 mg/mL, faintly hazy to hazy, colorless to faintly yellow

solubility

water: 0.90-1.10 mg/mL, slightly hazy to hazy, colorless to light yellow

solubility

water: soluble

solubility

water: soluble

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

300

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

color

white to yellow cast

color

white to faint yellow

color

-

color

off-white to faint yellow

Általános leírás

Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. They consist of lipid A moiety linked to an antigenic O-polysaccharide.
Proteus vulgaris is a rod-shaped Gram-negative, facultative anaerobe bacterium. It inhabits the intestinal tract of humans and animals and can be found in soil, water and feces.[1] P. vulgaris is a member of the Enterobacteriaceae family which are opportunistic pathogens in humans, responsible for urinary tract and burn infections.[2]
The chemical structures of LPS from Proteus sp. are different from each other.

Biokémiai/fiziológiai hatások

LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular patterns (PAMPs). Different chemical structures of LPS can be associated with the virulence and pathogenesis of the bacteria.[3][4][5] It has been reported that the LPS chemical structure from P. vulgaris can influence the crystallization of mineral urine components (such as calcium and magnesium), resulting in stone formation in the kidney.[6] Antibodies produced in rickettsial infections were found to react with LPS from Proteus vulgaris and Proteus mirabilis. This phenomenon allows the purified LPS from these two species to serve as a tool for the diagnosis of rickettsiosis (scrub typhus, caused by the bacterium Orientia sp.) in the Weil-Felix test.[7]

Egyéb megjegyzések

To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

kapcsolódó termék

Termékszám
Leírás
Árazás

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable


Válasszon a legfrissebb verziók közül:

Analitikai tanúsítványok (COA)

Lot/Batch Number

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Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Generation and characterization of a lipopolysaccharide-specific murine monoclonal antibody to Proteus vulgaris OX19
Bakshi, D., Jain, R., Tuteja, U., Batra, H.V.
World Journal of Microbiology & Biotechnology, 23, 817-821 (2007)
D J HOSSACK
British journal of pharmacology and chemotherapy, 19, 306-312 (1962-10-01)
Ascending urinary tract infections with stone formation have been produced experimentally in rats, using a modification of the method of Vermuelen & Goetz (1954a, b). A zinc disc infected with a culture of Proteus vulgaris was inserted into the bladder
LPS/TLR4 signal transduction pathway
Lu, Y.C., Yeh, W.C., Ohashi, P.S.
Cytokine, 42, 145-151 (2008)
S Mizushiri et al.
Microbiology and immunology, 34(2), 121-133 (1990-01-01)
The lipopolysaccharides (LPS) extracted from Proteus strains OX2, OX19, and OXK used as antigens in the Weil-Felix test, were characterized by chemical analysis and SDS-polyacrylamide gel electrophoresis (SDS-PAGE). To separate the O-polysaccharide, core-oligosaccharide, and lipid A moieties, each LPS was
A Torzewska et al.
FEMS immunology and medical microbiology, 31(3), 227-234 (2001-11-27)
The O-specific polysaccharide (O-antigen) of the lipopolysaccharide (LPS) of Proteus vulgaris O37 was studied by (1)H and (13)C nuclear magnetic resonance spectroscopy before and after O-deacetylation and found to be structurally similar to that of P. vulgaris O46 studied earlier.

Cikkek

Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.

Questions

1–2 of 2 Questions  
  1. What is the serotype of Proteus vulgaris used for this LPS?

    1 answer
    1. The serotype is OX19.

      Helpful?

  2. Which O-antigen does that P.vulgaris come with? And from which strain was the LPS isolated?

    1 answer
    1. The o-antigen is O-polysaccharide. The strain is considered proprietary. Please see the link below for additional information that may be helpful.
      https://pubmed.ncbi.nlm.nih.gov/9858461/

      The link below offers additional information to all of the lectin products, as well as a helpful selection guide:
      https://www.sigmaaldrich.com/technical-documents/technical-article/research-and-disease-areas/glycobiology/lectin-selection-guide-useful-guide-for-selecting-right-lectin#lectin

      Helpful?

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