SAB5701390

Anti- β-Catenin antibody produced in mouse

• UNSPSC kód: 12352203
• NACRES: NA.43
• klón: monoclonal
• application: WB
• faj reaktivitás: rat, human, mouse
• technika/technikák: western blot: 1:500-1:2000

Tulajdonságok

• biológiai forrás: mouse
• Minőségi szint: 100
• antitest terméktípus: primary antibodies
• klón: monoclonal
• Forma: liquid
• faj reaktivitás: rat, human, mouse
• koncentráció: 1.51 mg/mL
• technika/technikák: western blot: 1:500-1:2000
• UniProt elérési szám: P35222
• kiszállítva: wet ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... CTNNB1(1499)

Leírás

Általános leírás

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]

Immunogén

Recombinant protein of human β-Catenin.

Fizikai forma

Buffer: PBS with 0.05% sodium azide,0.2% BSA,40% glycerol,pH7.4.

Biztonsági adatok

• Tárolási osztály kódja: 12 - Non Combustible Liquids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable