SAB5701085

Anti- Caspase-3 antibody produced in rabbit

• UNSPSC kód: 12352203
• NACRES: NA.41

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• antitest terméktípus: primary antibodies
• klón: polyclonal
• form: liquid
• faj reaktivitás: human, rat, mouse
• koncentráció: 2.97 mg/mL
• technika/technikák: immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000
• UniProt elérési szám: P42574
• kiszállítva: wet ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... CASP3(836)

Leírás

Általános leírás

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

Immunogen

Recombinant protein of human Caspase-3.

Fizikai forma

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Biztonsági adatok

• Tárolási osztály kódja: 12 - Non Combustible Liquids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable