SAB4504031

Anti-phospho-IRF-3 (pSer³⁹⁶) antibody produced in rabbit

affinity isolated antibody

• UNSPSC kód: 12352203
• NACRES: NA.41

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• konjugátum: unconjugated
• antitest forma: affinity isolated antibody
• antitest terméktípus: primary antibodies
• klón: polyclonal
• form: buffered aqueous solution
• molekulatömeg: antigen 47 kDa
• faj reaktivitás: rat, mouse, human
• koncentráció: ~1 mg/mL
• technika/technikák: ELISA: 1:20000; western blot: 1:500-1:1000
• NCBI elérési szám: Q14653
• UniProt elérési szám: Q14653
• kiszállítva: wet ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: phosphorylation (pSer396)
• Géninformáció: human ... IRF3(3661)

Leírás

Általános leírás

IRF3 (interferon regulatory factor 3) is a transcription factor belonging to the IRF family and is involved in the innate immunity response against viruses and bacteria. The gene encoding IRF3 is localized on human chromosome 19q13.33.

Immunogen

The antiserum was produced against synthesized peptide derived from human IRF-3 around the phosphorylation site of Ser396.

Immunogen Range: 362-411

Alkalmazás

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Biokémiai/fiziológiai hatások

Activated IRF3 (interferon regulatory factor 3) influences the expression of type I interferons via the toll-like receptor (TLR3/4)-mediated signaling pathway. IRF3 can suppress glioma invasion, proliferation and migration. Studies have suggested that IRF3 may have characteristics of tumor suppression.

Tulajdonságok és előnyök

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Fizikai forma

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable