SAB4200734

Anti-IL6 high affinity antibody, Mouse monoclonal

clone IL6-2A3, purified from hybridoma cell culture

• Szinonimák: Anti-B-cell stimulatory factor 2 (BSF-2), Anti-CTL differentiation factor (CDF), Anti-Hybridoma growth factor, Anti-Interferon beta-2 (IFN-beta-2), Anti-Interleukin-6
• UNSPSC kód: 12352203
• NACRES: NA.41
• klón: IL6-2A3, monoclonal
• application: ELISA; IP
• faj reaktivitás: human
• technika/technikák: ELISA: suitable; immunoblotting: 0.125-0.25 μg/mL using recombinant human IL6 expressed in HEK-293T cells; immunoprecipitation (IP): 10-20 μg/test using concentrated supernatant of human osteosarcoma MG-63 cells treated with IL1β
• citations: 2

Tulajdonságok

• biológiai forrás: mouse
• Minőségi szint: 200
• antitest forma: purified from hybridoma cell culture
• antitest terméktípus: primary antibodies
• klón: IL6-2A3, monoclonal
• Forma: buffered aqueous solution
• faj reaktivitás: human
• koncentráció: ~1.0 mg/mL
• technika/technikák: ELISA: suitable; immunoblotting: 0.125-0.25 μg/mL using recombinant human IL6 expressed in HEK-293T cells; immunoprecipitation (IP): 10-20 μg/test using concentrated supernatant of human osteosarcoma MG-63 cells treated with IL1β
• izotípus: IgG2a
• UniProt elérési szám: P05231
• kiszállítva: dry ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... IL6(3569)

Leírás

Általános leírás

Interleukin-6 (IL6) is a multifunctional cytokine.

Immunogén

recombinant human IL6

Alkalmazás

Anti-IL6 high affinity antibody, Mouse monoclonal has been used in

• immunoblotting
• immunoprecipitation
• ELISA

Biokémiai/fiziológiai hatások

Interleukin-6 (IL6) plays a wide variety of important biological roles in the immune, nervous and endocrine system. It is an essential component for hybridoma growth and is found in many supplemental cloning media. IL6 regulates acute and chronic inflammatory diseases and has been proven to be an excellent target for clinical treatment against autoimmune disorders such as rheumatoid arthritis, juvenile idiopathic arthritis and Castleman′s disease. IL6 also plays a key role in the pathogenesis of multiple myeloma.

Fizikai forma

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable