SAB1300367

Anti-Aurora-C (N-term M1) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Szinonimák: Anti-Aurora-C, Anti-Aurora/Ipl1-related kinase 3, Anti-Aurora/Ipl1/Eg2 protein 2, Anti-Serine/threonine protein kinase 13
• UNSPSC kód: 12352203
• NACRES: NA.41

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• konjugátum: unconjugated
• antitest forma: IgG fraction of antiserum
• antitest terméktípus: primary antibodies
• klón: polyclonal
• form: buffered aqueous solution
• faj reaktivitás: human
• technika/technikák: indirect ELISA: 1:1000; indirect immunofluorescence: 1:10-1:50; western blot: 1:100-1:500
• NCBI elérési szám: NP_003151
• UniProt elérési szám: Q9UQB9
• kiszállítva: dry ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... AURKC(6795)

Leírás

Általános leírás

Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.

Immunogen

AURORAC (Q9UQB9, 1-30)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Aurora-C.

Fizikai forma

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: nwg
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable