PRS3335
Anti-Bcl-2 (ab1) antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
Szinonimák:
Anti-B-cell CLL/lymphoma 2
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(4)
About This Item
konjugátum:
unconjugated
application:
ELISA (i)
IF
IHC
WB
IF
IHC
WB
klón:
polyclonal
faj reaktivitás:
human, mouse
citations:
13
technika/technikák:
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
Javasolt termékek
biológiai forrás
rabbit
Minőségi szint
konjugátum
unconjugated
antitest forma
affinity isolated antibody
antitest terméktípus
primary antibodies
klón
polyclonal
Forma
buffered aqueous solution
faj reaktivitás
human, mouse
technika/technikák
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt elérési szám
kiszállítva
dry ice
tárolási hőmérséklet
−20°C
célzott transzláció utáni módosítás
unmodified
Géninformáció
human ... BCL2(596)
Related Categories
Általános leírás
B-cell lymphoma 2 (BCL2), a proto-oncogene is made of three exons. It is widely expressed in immature B-cells and memory B cells. BCL2 is found at high levels in the thymus, spleen, and lymph nodes. BCL2 gene is mapped to human chromosome 18q21.33.
Immunogén
a peptide corresponding to 15 amino acids near the N-terminus of human Bcl-2.
Alkalmazás
Anti-Bcl-2 (ab1) antibody produced in rabbit has been used in western blotting (1:100) (1:1000), immunohistochemistry (1:50), immunoprecipitation (IP) (1:1000)
Biokémiai/fiziológiai hatások
B-cell lymphoma 2 (BCL2) plays a key role in maintaining the integrity of the mitochondrial membrane. It blocks the release of cytochrome C and its binding to apoptosis activating factor-1 (APAF1). BCL2 family proteins participate in modulating cell death. It also regulates apoptosis, necrosis, and autophagy. Upregulation of BCL2 is seen in several human cancers. Overexpression of BCL2 is observed in chronic lymphocytic leukemia (CLL), marginal cell lymphoma, and mantle cell lymphoma.
Kapcsolódás
The action of this antibody can be blocked using blocking peptide SBP3335.
Fizikai forma
Solution in phosphate buffered saline containing 0.02% sodium azide
Jogi nyilatkozat
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Nem találja a megfelelő terméket?
Próbálja ki a Termékválasztó eszköz. eszközt
javasolt
kapcsolódó termék
Product No.
Leírás
Árazás
Tárolási osztály kódja
10 - Combustible liquids
WGK
WGK 2
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Válasszon a legfrissebb verziók közül:
Analitikai tanúsítványok (COA)
Lot/Batch Number
Nem találja a megfelelő verziót?
Ha egy adott verzióra van szüksége, a tétel- vagy cikkszám alapján rákereshet egy adott tanúsítványra.
Már rendelkezik ezzel a termékkel?
Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.
Yudi Han et al.
International journal of molecular medicine, 41(2), 800-808 (2017-12-06)
Autophagy may be a major mechanism by which osteoblasts (OBs) protect against the negative effects of chronic glucocorticoid (GC) usage. OBs are closely associated with the remodeling that occurs in GC‑induced osteoporosis (GIO). In osteocytes, in response to stress induced by GCs, several
Qiang Zhang et al.
Chinese medical journal, 135(9), 1076-1086 (2022-02-23)
Fibrosis in the peripheral airways contributes to airflow limitation in patients with chronic obstructive pulmonary disease (COPD). However, the key proteins involved in its development are still poorly understood. Thus, we aimed to identify the differentially expressed proteins (DEPs) between
Leilei Yu et al.
Experimental and therapeutic medicine, 12(4), 2275-2280 (2016-10-05)
Diabetes is a metabolic disease that results from impairment in insulin secretion. The present study aimed to investigate the potential role of NOM1 in the function of pancreatic islet β cells and insulin secretion. MIN6 cells isolated from mice were
Zhihai Yuan et al.
Journal of biochemical and molecular toxicology, 36(9), e23138-e23138 (2022-07-16)
Glioma is the foremost recurrent type of brain tumor in humans; in particular, glioblastoma (GBM) is the main form of brain tumor (GBM) that is highly proliferative and impervious to apoptosis. Triphlorethol-A (TA), a phlorotannin isolated from Ecklonia cava, exhibited cytoprotective, antioxidant, and anticancer properties. However
Ping He et al.
International journal of molecular medicine, 45(4), 1261-1269 (2020-03-04)
The authors' previous studies demonstrated that the major renal damage from hepatitis B virus infection is HBx‑induced apoptosis of renal tubular epithelial cells. Cordyceps sinensis is one of the most valuable of traditional Chinese medicines and is extensively used to treat
Tudóscsoportunk valamennyi kutatási területen rendelkezik tapasztalattal, beleértve az élettudományt, az anyagtudományt, a kémiai szintézist, a kromatográfiát, az analitikát és még sok más területet.
Lépjen kapcsolatba a szaktanácsadással