Ugrás a tartalomra
Merck

77140

Sigma-Aldrich

Peptidoglycan from Staphylococcus aureus

cell wall component

Szinonimák:

Peptidoglycan from S. aureus

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

MDL-szám:
UNSPSC kód:
12352201
NACRES:
NA.32

Minőségi szint

Forma

lyophilized powder

oldhatóság

soluble, hazy to turbid, colorless to faintly yellow

tárolási hőmérséklet

−20°C

Alkalmazás

Peptidoglycan from Staphylococcus aureus has been used:
  • for the stimulation of lymphocytes: peptidoglycan activates the toll-like receptor 2 (TLR2), present in mammalian cells. It works as an antagonist of Poly (I:C)
  • for g-type lysozyme stimulation by intraperitoneally inoculating it into sole specimens
  • in phosphate buffer saline and injected into Labeo rohita fingerlings, to study its effect on nucleotide-binding oligomerization domain-2 (NOD-2) gene expression

Biokémiai/fiziológiai hatások

The cell wall of gram positive bacteria is largely made up of peptidoglycan. It is composed of polysaccharide chains interlinked by peptide bridges. This peptidoglycan gives a certain rigidity to the cell wall and gives the cell mechanical strength. It is a surface molecule which is known to stimulate immune reactions including cytokine production to fever.

Kiszerelés

Bottomless glass bottle. Contents are inside inserted fused cone.

Egyéb megjegyzések

Major component of the cell wall in gram positive organisms. Consists of a glycan backbone with alternating β 1-4 linked residues of N-acetyl-D-glucosamine and muramic acid. The immunological activities of bacterial peptidoglycans; Peptidoglycan types of bacterial cell walls and their taxonomic implications; Antibody response to peptidoglycan during staphylococcal infections

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Egyéni védőeszköz

Eyeshields, Gloves, type N95 (US)


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Analitikai tanúsítványok (COA)

Lot/Batch Number

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Dokumentumtár megtekintése

Sara Abouelasrar Salama et al.
Mediators of inflammation, 2020, 6087109-6087109 (2020-07-23)
The serum amyloid A (SAA) gene family is highly conserved and encodes acute phase proteins that are upregulated in response to inflammatory triggers. Over the years, a considerable amount of literature has been published attributing a wide range of biological
Molecular characterization of nucleotide binding and oligomerization domain (NOD)-2, analysis of its inductive expression and down-stream signaling following ligands exposure and bacterial infection in rohu (Labeo rohita)
Swain B, et al.
Developmental and Comparative Immunology, 36(1), 93-103 (2012)
ABC transporters involved in the biogenesis of the outer membrane in gram-negative bacteria
Narita S
Bioscience, Biotechnology, and Biochemistry, 75(6), 1044-1054 (2011)
Peptidoglycan types of bacterial cell walls and their taxonomic implications.
K H Schleifer et al.
Bacteriological reviews, 36(4), 407-477 (1972-12-01)
Xue Kong et al.
Frontiers in physiology, 9, 1476-1476 (2018-11-09)
Vesicomyidae clams are common species living in cold seeps, which incorporates symbiotic bacteria into their body maintaining endosymbiosis relationship. As members of pattern recognition receptor (PRR) family, peptidoglycan recognition proteins (PGRPs) recognize pathogen associated molecular patterns and play an important

Cikkek

Peptidoglycan structure: alternating GlcNAc and N-acetylmuramic acid cross-linked to peptides form the basic backbone.

Peptidoglikán szerkezet: peptidekkel keresztkötésben lévő GlcNAc és N-acetil-muraminsav váltakozva alkotja az alapgerincet.

Tudóscsoportunk valamennyi kutatási területen rendelkezik tapasztalattal, beleértve az élettudományt, az anyagtudományt, a kémiai szintézist, a kromatográfiát, az analitikát és még sok más területet.

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