In the Rat Kidney Tox panel, the testing of 4 mouse urine samples revealed the presence of EGF, Albumin, Clusterin, OPN, and a1-microglobulin in at least 1 out of the 4 samples. However, it cannot be concluded definitively that there is no cross reactivity to NGAL or Cystatin C as the absence of signal may be attributed to low levels in the few samples tested.
RKTX2MAG-37K
MILLIPLEX® Rat Kidney Toxicity Magnetic Bead Panel 2 - Toxicity Multiplex Assay
The analytes available for this multiplex kit are: Albumin, AGP, ß2M, Cystatin C, EGF, Lipocalin-2/NGAL.
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(2)
About This Item
UNSPSC kód:
12161503
eCl@ss:
32161000
NACRES:
NA.84
To order a Milliplex® kit, please search for your analyte of interest.
Javasolt termékek
Minőségi szint
faj reaktivitás
rat
gyártó/kereskedő neve
Milliplex®
assay range
accuracy: 70-123%
standard curve range: 0.00-2 ng/mL
(EGF)
standard curve range: 0.01-10 ng/mL
(Lipocalin-2/NGAL)
standard curve range: 0.01-8 ng/mL
(Cystatin C)
standard curve range: 0.48-350 ng/mL
(β2M)
standard curve range: 1.37-1,000 ng/mL
(AGP)
standard curve range: 10.97-8,000 ng/mL
(Albumin)
inter-assay cv: <15%
intra-assay cv: <10%
(All other analytes)
inter-assay cv: <20%
intra-assay cv: <15%
(AGP)
technika/technikák
multiplexing: suitable
észlelési módszer
fluorometric (Luminex xMAP)
kiszállítva
wet ice
Általános leírás
MILLIPLEX® Rat Kidney Toxicity Bead Panels 1 & 2, coupled with the Luminex® xMAP®platform in a bead format, enables you to focus on discovery so you receive the advantage of ideal speed and sensitivity, allowing quantitative multiplex detection of multiple analytes simultaneously, dramatically improving productivity.
Panel Type: Toxicity
Panel Type: Toxicity
Egyediség
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.
Alkalmazás
- Analytes: Alpha-1 Acid Glycoprotein (AGP), Albumin, ß2M, Cystatin C, EGF, Lipocalin-2/NGAL
- Recommended Sample type: urine
- Recommended Sample dilution: 1:500
- Assay Run Time: Overnight
- Research Category: Toxicity
Tulajdonságok és előnyök
Design your multiplex kit by choosing available analytes within this panel.
Kiszerelés
Everything you need in a single kit.
Tárolás és stabilitás
Recommended storage for kit components is 2 - 8°C.
Egyéb megjegyzések
Sensitivity: See kit protocol for individual analytes sensitivities.
Jogi információk
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Jogi nyilatkozat
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Figyelmeztetés
Danger
Figyelmeztető mondatok
Óvintézkedésre vonatkozó mondatok
Veszélyességi osztályok
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Célzott szervek
Respiratory system
Tárolási osztály kódja
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Analitikai tanúsítványok (COA)
Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.
Már rendelkezik ezzel a termékkel?
Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.
Michael J Coyne et al.
PloS one, 17(5), e0269085-e0269085 (2022-05-28)
Symmetric dimethylarginine (SDMA) is a serum biomarker of excretory renal function which consistently correlates with glomerular filtration rate (GFR) across multiple species including rats, dogs, and humans. In human and veterinary clinical settings SDMA demonstrates enhanced sensitivity for detection of
Mónica Ríos-Silva et al.
Molecules (Basel, Switzerland), 24(1) (2018-12-26)
Capsaicin is an agonist of the transient receptor potential vanilloid type 1 (TRPV1) channel, which has been related to the pathophysiology of kidney disease secondary to diabetes. This study aimed to evaluate the chronic effect of capsaicin administration on biomarkers
Kidney biomarkers in MCPA-induced acute kidney injury in rats: reduced clearance enhances early biomarker performance.
Wunnapuk, K; Liu, X; Gobe, GC; Endre, ZH; Peake, PW; Grice, JE; Roberts, MS; Buckley, NA
Toxicology Letters null
Iwan P Williams et al.
mAbs, 12(1), 1685349-1685349 (2019-11-27)
IgE monoclonal antibodies hold great potential for cancer therapy. Preclinical in vivo systems, particularly those in which the antibody recognizes the host species target antigen and binds to cognate Fc receptors, are often the closest approximation to human exposure and
Nadeeka S Udawatte et al.
Frontiers in pharmacology, 11, 511-511 (2020-05-12)
Candida albicans is the major fungal species associated with superficial mucosal infections such as oral candidiasis as well as systemic mycoses with high morbidity and mortality. On top of the rising drug resistance, currently available antifungal agents have significant adverse
Related Content
Novel kidney toxicity biomarkers expand options for acute nephrotoxicity detection. Multiplex assays measure multiple renal damage biomarkers in small sample volumes, minimizing time and costs. See how MILLIPLEX® multiplex kidney toxicity assays detected vancomycin-induced subacute nephrotoxicity in rat models.
Multiplex toxicity assays enable researchers to simultaneously measure multiple toxicity biomarkers of various organs to gain a better understanding of toxicity. Explore how MILLIPLEX® multiplex toxicity assays are advancing research on liver injury, kidney toxicity, genotoxicity, and more.
-
Does the Milliplex rat kit RKTX2MAG cross-react with mouse?
1 answer-
Helpful?
-
Active Filters
Tudóscsoportunk valamennyi kutatási területen rendelkezik tapasztalattal, beleértve az élettudományt, az anyagtudományt, a kémiai szintézist, a kromatográfiát, az analitikát és még sok más területet.
Lépjen kapcsolatba a szaktanácsadással
