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Merck
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Fontos dokumentumok

MABE167

Sigma-Aldrich

Anti-SNAI1 Antibody, clone 10H4.1

clone 10H4.1, from mouse

Szinonimák:

Zinc finger protein SNAI1, Protein snail homolog 1, Protein sna

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

UNSPSC kód:
12352203
eCl@ss:
32160702
NACRES:
NA.41
klón:
10H4.1, monoclonal
application:
IHC
WB
faj reaktivitás:
human, rat, mouse
technika/technikák:
immunohistochemistry: suitable
western blot: suitable
citations:
5

biológiai forrás

mouse

Minőségi szint

antitest forma

purified immunoglobulin

antitest terméktípus

primary antibodies

klón

10H4.1, monoclonal

faj reaktivitás

human, rat, mouse

technika/technikák

immunohistochemistry: suitable
western blot: suitable

izotípus

IgMκ

NCBI elérési szám

UniProt elérési szám

kiszállítva

wet ice

célzott transzláció utáni módosítás

unmodified

Géninformáció

human ... SNAI1(6615)

Általános leírás

SNAI1, also known as Snail homolog 1, is a transcription factor that down regulates the expression of ectodermal genes within the mesoderm and is thought to be essential for mesoderm formation in the developing embryo. SNAI1 is expressed in the kidney and in mesenchymal and epithelial cell lines. Mutations in SNAI1 have been associated with tumors.

Immunogén

Epitope: N-terminus
KLH-conjugated linear peptide corresponding to the N-terminus of Human SNAIL1.

Alkalmazás

Anti-SNAI1 Antibody, clone 10H4.1 is a highly specific mouse monoclonal antibody, that targets Zinc Finger Protein & has been tested in western blotting & IHC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Western Blotting Analysis: 0.5 µg/mL from a representative lot detected SNAIL1 in 10 µg of human and mouse kidney tissue lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SNAIL1 in human kidney section and human tonsil section tissues.

Minőség

Evaluated by Western Blotting in rat kidney tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected SNAIL1 in 10 µg of rat kidney tissue lysate.

Cél megnevezése

~29 kDa observed

Fizikai forma

Format: Purified
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.

Tárolás és stabilitás

Stable for 1 year at 2-8°C from date of receipt.

Egyéb megjegyzések

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Tárolási osztály kódja

10 - Combustible liquids

WGK

WGK 2

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable


Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

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Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Li-Ting Wang et al.
EMBO reports, 21(2), e48795-e48795 (2020-01-08)
Epigenetic regulation is important for cancer progression; however, the underlying mechanisms, particularly those involving protein acetylation, remain to be fully understood. Here, we show that p300/CBP-associated factor (PCAF)-dependent acetylation of the transcription factor intestine-specific homeobox (ISX) regulates epithelial-mesenchymal transition (EMT)
Jia-Xing Sun et al.
Angiogenesis, 21(3), 635-652 (2018-04-21)
Ocular neovascularization is a comprehensive process involved in retinal vascular development and several blinding diseases such as age-related macular degeneration and retinopathy of prematurity, with vascular endothelial growth factor (VEGF) regarded as the master regulator. However, the qualified effect of
Jeong Ae Park et al.
PLoS genetics, 11(7), e1005324-e1005324 (2015-07-07)
Vascular branching morphogenesis is activated and maintained by several signaling pathways. Among them, vascular endothelial growth factor receptor 2 (VEGFR2) signaling is largely presented in arteries, and VEGFR3 signaling is in veins and capillaries. Recent reports have documented that Snail
Menggui Huang et al.
Nature cardiovascular research, 1(4), 372-388 (2022-05-17)
Myocardial infarction (MI) is a leading cause of death worldwide, largely because efficient interventions to restore cardiac function after MI are currently lacking. Here, we characterize vascular aberrancies induced by MI, and propose to target acquired endothelial cell (EC) changes
Hemin-Induced Endothelial Dysfunction and Endothelial to Mesenchymal Transition in the Pathogenesis of Pulmonary Hypertension Due to Chronic Hemolysis.
Gonzales, et al.
International Journal of Molecular Sciences, 23 (2023)

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