MAB4444

Anti-Epithelial Cell Adhesion Molecule (EpCAM) Antibody, clone 8

clone mab 8, from mouse

• Szinonimák: Adenocarcinoma-associated antigen, CD326 antigen, Cell surface glycoprotein Trop-1, Epithelial cell surface antigen, Epithelial glycoprotein, KS 1/4 antigen, Major gastrointestinal tumor-associated protein GA733-2, antigen identified by monoclonal antibo
• UNSPSC kód: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• klón: mab 8, monoclonal
• application: FACS; ICC; WB
• faj reaktivitás: human
• technika/technikák: flow cytometry: suitable; immunocytochemistry: suitable; western blot: suitable

Tulajdonságok

• biológiai forrás: mouse
• Minőségi szint: 100
• antitest forma: purified immunoglobulin
• klón: mab 8, monoclonal
• faj reaktivitás: human
• technika/technikák: flow cytometry: suitable; immunocytochemistry: suitable; western blot: suitable
• izotípus: IgG2aκ
• NCBI elérési szám: NP_002345.2
• UniProt elérési szám: P16422
• kiszállítva: wet ice
• célzott transzláció utáni módosítás: unmodified

Leírás

Általános leírás

Epithelial Call Adhesion Molecule (EpCAM, CD326) is a transmembrane glycoprotein of approximately 40 kDa. EpCAM was initially identified as a tumor associated marker having high expression in quickly proliferating epithelial tumors. As such, EpCAM has been of significant interest as a means for tumor diagnosis and therapy. EpCAM is also expressed in normal epithelial cells, but in comparatively lower levels. Preliminary studies limited EpCAM’s function to cell-cell adhesion; however more recent studies indicate it to be involved in diverse processes that include cell migration, cell signaling, differentiation and proliferation.

Egyediség

This antibody recognizes epithelial cell adhesion molecule (EpCAM), specifically on undifferentiated human embryonic stem cells.

Immunogén

Epitope: Unknown

HES-3 Cells (Choo, et al. (2008) Stem Cells. Jun;26(6):1454-63)

Alkalmazás

Flow Cytometry Analysis: 0.5 µg from a previous lot detected Epithelial cell adhesion molecule in human embryonic stem cells.

Western Blot Analysis: A previous lot was used by an independent laboratory in WB. (Ng, V., et al., 2010)

Research Category
Stem Cell Research

Research Sub Category
Pluripotent & Early Differentiation

Adhesion (CAMs)

This Anti-Epithelial Cell Adhesion Molecule (EpCAM) Antibody, clone 8 is validated for use in FC, IC, WB for the detection of Epithelial Cell Adhesion Molecule (EpCAM).

Minőség

Evaluated by Immunocytochemistry in human embryonic stem cells.

Immunocytochemistry Analysis: 1-10 µg/mL from a previous lot detected epithelial cell adhesion molecule (EpCAM) in human embryonic stem cells.

Cél megnevezése

~ 40 kDa

Fizikai forma

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

Tárolás és stabilitás

Stable for 1 year at 2-8°C from date of receipt.

Analízis megjegyzés

Control
Human embryonic stem cells

Egyéb megjegyzések

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biztonsági adatok

• Tárolási osztály kódja: 12 - Non Combustible Liquids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable