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Merck
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MAB1430

Sigma-Aldrich

Anti-Collagen Type IV Antibody, clone 24.12.8 (PHM-12)

clone 24.12.8 (PHM-12), Chemicon®, from mouse

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

UNSPSC kód:
12352203
eCl@ss:
32160702
NACRES:
NA.41
klón:
24.12.8 (PHM-12), monoclonal
application:
IHC (p)
faj reaktivitás:
human
technika/technikák:
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
citations:
10

biológiai forrás

mouse

Minőségi szint

antitest forma

purified immunoglobulin

klón

24.12.8 (PHM-12), monoclonal

faj reaktivitás

human

gyártó/kereskedő neve

Chemicon®

technika/technikák

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable

izotípus

IgG1

UniProt elérési szám

kiszállítva

wet ice

célzott transzláció utáni módosítás

unmodified

Általános leírás

BIOCHEMISTRY:

p I = 5.5

Egyediség

MAB1430 provides a marker for an antigen known to be important in glomerular cell-matrix interactions, and should prove useful in research into the mechanisms involved in renal pathology. This antibody reacts with glomerular and tubular basement membranes in kidney as well as basal lamina of capillaries. It also labels mesangial cells and matrix within the glomerulus as well as basement membrane structures in all organs examined (Gusterson et al., 1984).

Immunogén

Human glomeruli

Alkalmazás

Detect Collagen Type IV using this Anti-Collagen Type IV Antibody, clone 24.12.8 (PHM-12) validated for use in IH, IH(P).
The antibody is suitable for use on both frozen and protease digested paraffin processed tissue.

SUGGESTED USAGE

Indirect immunoperoxidase staining - the final dilution will depend on the assay conditions and detection system employed. However, a dilution of at least 1:40 will be applicable to most commonly used systems.

Optimal working dilutions must be determined by the end user.

Fizikai forma

Format: Purified
Purified immunoglobulin presented as a liquid in phosphate buffered saline, pH 7.4, containing 0.2% bovine serum albumin and 0.1% sodium azide.

Tárolás és stabilitás

Store at 2 to 8°C, for up to 6 months. For prolonged periods, store below -20°C in undiluted aliquots. AVOID REPEATED FREEZE/THAW CYCLES.

WARNING: The monoclonal reagent solution contains 0.1% sodium azide as a preservative. Due to potential hazards arising from the build up of this material in pipes, spent reagent should be disposed of with liberal volumes of water.

Egyéb megjegyzések

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Jogi információk

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Tárolási osztály kódja

12 - Non Combustible Liquids

WGK

WGK 2

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable


Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

Már rendelkezik ezzel a termékkel?

Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Functional characterization of cancer-associated fibroblasts of human cutaneous squamous cell carcinoma.
Suzan Commandeur,Suet Huy Ho,Frank R de Gruijl,Rein Willemze,Cornelis P Tensen et al.
Experimental Dermatology null
Fibroblasts facilitate re-epithelialization in wounded human skin equivalents.
El Ghalbzouri, Abdoelwaheb, et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 84, 102-112 (2004)
Invading squamous cell carcinoma can retain a basal lamina. An immunohistochemical study using a monoclonal antibody to type IV collagen.
Gusterson, B A, et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 51, 82-87 (1984)
Production of monoclonal antibodies to fibronectin, type IV collagen and other antigens of the human glomerulus.
Hancock, W W, et al.
Pathology, 16, 197-206 (1984)
S E Aggrey et al.
Poultry science, 73(12), 1822-1828 (1994-12-01)
Records of 1,530 Japanese quail were used to estimate heritabilities and genetic correlations based on a derivative-free restricted maximum likelihood (REML) method with an animal model and ANOVA. The animal model included fixed effects of hatch and sex, random effects

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