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EZHS42

Millipore

Human Amyloid β42 ELISA Kit

measures and quantifies Amyloid β42 levels in 50 μL CSF, cell culture supernatent or plasma

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
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About This Item

UNSPSC kód:
12161503
eCl@ss:
32161000
NACRES:
NA.84

Terméknév

High Sensitivity Human Amyloid β42 ELISA, This High Sensitivity Human Amyloid β42 ELISA is used to measure & quantify Amyloid β42 levels in Neuroscience research.

Minőségi szint

200

faj reaktivitás

human

kiszerelés

kit of 1 × 96 wells

parameter

50 μL sample volume (Overnight assay)

assay range

sensitivity: 8.0 pg/mL
(50 μl sample size)
standard curve range: 16-500 pg/mL

technika/technikák

ELISA: suitable

bemenet

sample type plasma (K2 EDTA)
sample type serum
sample type cerebrospinal fluid (CSF)

alkalmazás(ok)

research use

észlelési módszer

colorimetric (450nm/590nm)

kiszállítva

wet ice

tárolási hőmérséklet

2-8°C

Géninformáció

human ... APP(351)

Általános leírás

Amyloid beta peptides have been implicated in the etiology of Alzheimer’s disease. Amyloid beta 40 is the most prominent peptide and Amyloid beta 42 is the neurotoxic form. The Amyloid beta 42/40-ratio (AB ratio) has been reported as a better indicator of the Alzheimer pathology. Millipore’s High Sensitivity Human Amyloid β42 ELISA kit is used for the measurement of Amyloid β42 in cerebrospinal fluid, cell culture supernatants, primary neurons and plasma in a 96-well format.

Egyediség

The Amyloid β42 ELISA (HS) uses monoclonal anti-Aβ antibodies with high selectivity for human Aβ. The capture antibody recognizes the C-terminal end of Amyloid β1-42, which causes a high selectivity for Aβ42. The cross-reactivity of the used antibodies to other Amyloid peptides was tested by ELISA and BIACORE and shows no significant cross-reactivity to Aβ1-38, Aβ1-39, Aβ1-40, Aβ1-43 and Aβ1-44.

Alkalmazás

Research Category
Neuroscience
Research Sub Category
Alzheimer′s Disease
This High Sensitivity Human Amyloid β42 ELISA is used to measure & quantify Amyloid β42 levels in Neuroscience research.
This assay requires 50 µl of sample and is an overnight assay.
Used to detect/quantify: Amyloid β42

Tárolás és stabilitás

Components in the kit can be stored up to 2 weeks at 2-8°C

Egyéb megjegyzések

Please contact Technical Service for linearity of dilution.

Jogi nyilatkozat

For research use only. Not for use in diagnostic procedures.

Piktogramok

CorrosionExclamation mark
GHS05,GHS07

Figyelmeztetés

Warning

Figyelmeztető mondatok

H290,H317,H412

Óvintézkedésre vonatkozó mondatok

P234 - P261 - P272 - P273 - P280 - P302 + P352

Veszélyességi osztályok

Aquatic Chronic 3 - Met. Corr. 1 - Skin Sens. 1

Tárolási osztály kódja

8A - Combustible corrosive hazardous materials

Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

Már rendelkezik ezzel a termékkel?

Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Sooah Jang et al.
Psychiatry investigation, 15(2), 205-213 (2018-02-25)
Conventional methods for organotypic hippocampal tissue slice culture (OHSC) have shown several disadvantages or limitations regarding age of animals used, duration of culture and difficulty using neurodegenerative models. Therefore, we tried to establish OHSC from old 3xTg-Alzheimer's disease (AD) mice
Teresa Niccoli et al.
Current biology : CB, 26(17), 2291-2300 (2016-08-16)
Glucose hypometabolism is a prominent feature of the brains of patients with Alzheimer's disease (AD). Disease progression is associated with a reduction in glucose transporters in both neurons and endothelial cells of the blood-brain barrier. However, whether increasing glucose transport
Ekram Abdel Salam et al.
Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology, 33(1), 13-18 (2014-05-21)
The presence of non-progressive cognitive impairment is recognized as a common feature in a substantial proportion of patients with Duchenne muscular dystrophy (DMD). Concurrently, the amyloid beta peptide (Aβ42) protein has been associated with changes in memory and cognitive functions.
Gunjan Manocha et al.
Current Alzheimer research, 15(12), 1123-1135 (2018-08-03)
Alzheimer's disease (AD) is associated with age-associated central nervous system degeneration and dementia. This decline in the function correlates with deposition of Aβ peptide containing plaques and associated reactive gliosis. The inflammatory phenotype of microglia, in particular, is often considered
Nataliya Golovyashkina et al.
Molecular neurodegeneration, 10, 60-60 (2015-11-07)
Dendritic simplification, a key feature of the neurodegenerative triad of Alzheimer's disease (AD) in addition to spine changes and neuron loss, occurs in a region-specific manner. However, it is unknown how changes in dendritic complexity are mediated and how they
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