AG964
β Amyloid 1-40, aβ, ultra pure, NaOH, recombinant human
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)
About This Item
UNSPSC kód:
12352202
eCl@ss:
32160405
NACRES:
NA.77
Javasolt termékek
biológiai forrás
human
Minőségi szint
Teszt
98%
form
powder
gyártó/kereskedő neve
Chemicon®
NCBI elérési szám
UniProt elérési szám
Géninformáció
human ... APP(351)
Általános leírás
Beta Amyloid (1-40), ultra pure, NaOH.
MOL. WT.: 4329.6 Da by Mass Spec Analysis (theoretical 4329.86)
SEQUENCE: Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
PEPTIDE CONTENT: 1 mg per vial.
COUNTER ION: NaOH
MOL. WT.: 4329.6 Da by Mass Spec Analysis (theoretical 4329.86)
SEQUENCE: Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
PEPTIDE CONTENT: 1 mg per vial.
COUNTER ION: NaOH
Alkalmazás
Different researchers claim enhanced activity due to different salts.
The TFA salt is what has been the industry standard.
The HFIP makes the beta-amyloid homogenously monomeric.
The NaOH apparently make it monomeric too and is also water soluble, which the TFA salt and HFIP are not.
The HCl salt is supposed to be more biological, as TFA is not found in the body.
By offering the different salts, it lets the researchers duplicate the different assays that have been developed by other researchers (see below).
TFA: Shu-chuan Jao, S-C, et. al. 1997, Amyloid; Int J Exp. Clinical Invest. 4, 231
HFIP: Stine, W.B. et. al. 2003, J. Biol. Chem, 278, 11612
NaOH: Fezoui, Y., et. al. 2000, Amyloid, 7, 166
HCL: Kanek, I and Tutumi, S., 1997, J. Neurochem, 68, 438
The TFA salt is what has been the industry standard.
The HFIP makes the beta-amyloid homogenously monomeric.
The NaOH apparently make it monomeric too and is also water soluble, which the TFA salt and HFIP are not.
The HCl salt is supposed to be more biological, as TFA is not found in the body.
By offering the different salts, it lets the researchers duplicate the different assays that have been developed by other researchers (see below).
TFA: Shu-chuan Jao, S-C, et. al. 1997, Amyloid; Int J Exp. Clinical Invest. 4, 231
HFIP: Stine, W.B. et. al. 2003, J. Biol. Chem, 278, 11612
NaOH: Fezoui, Y., et. al. 2000, Amyloid, 7, 166
HCL: Kanek, I and Tutumi, S., 1997, J. Neurochem, 68, 438
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neurodegenerative Diseases
Fizikai forma
White lyophilized powder. Resuspend in 1% NH4OH at a concentration of 1 mg/mL. Sonicate for 30 seconds to 1 minute after it has gone into solution. To bring into your solution: After resuspension, add 5x or 10x buffer stock (PBS, TBS) and water to bring to 1x buffer.
Tárolás és stabilitás
Maintain lyophilized material at -20ºC for up to 12 months after date of receipt. After reconstitution maintain at -20ºC to -70ºC for up to 2 weeks in undiluted aliquots. Avoid freeze/thaw cycles to avoid aggregation.
Egyéb megjegyzések
Please refer to the Certificate of Analysis for the lot-specific Molecular weight.
Jogi információk
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Jogi nyilatkozat
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Tárolási osztály kódja
11 - Combustible Solids
WGK
WGK 3
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Analitikai tanúsítványok (COA)
Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.
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