ABC426

Anti-ATP-citrate synthase/ACLY Antibody

from rabbit, purified by affinity chromatography

• Szinonimák: ATP-citrate synthase, ATP-citrate (pro-S-)-lyase, ACL, Citrate cleavage enzyme
• UNSPSC kód: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• klón: polyclonal
• application: IHC; WB
• faj reaktivitás: mouse, rat, human
• technika/technikák: immunohistochemistry: suitable; western blot: suitable
• citations: 1

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• antitest forma: affinity isolated antibody
• antitest terméktípus: primary antibodies
• klón: polyclonal
• tisztítva: affinity chromatography
• faj reaktivitás: mouse, rat, human
• faj reaktivitás (homológia által előrejelzett): bovine (based on 100% sequence homology), sheep (based on 100% sequence homology), porcine (based on 100% sequence homology)
• technika/technikák: immunohistochemistry: suitable; western blot: suitable
• NCBI elérési szám: NP_001087
• UniProt elérési szám: P53396
• kiszállítva: wet ice
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... ACLY(47)

Leírás

Általános leírás

ATP citrate synthase, also known as ATP-citrate (pro-S-)-lyase (ACL) or Citrate cleavage enzyme, and encoded by the gene name ACLY is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine.

Immunogén

Epitope: Unknown

KLH-conjugated linear peptide corresponding to human ATP-citrate synthase/ACLY.

Alkalmazás

Anti-ATP-citrate synthase/ACLY Antibody | ABC426 is an antibody against ATP-citrate synthase/ACLY Antibody for use in Western Blotting, Immunohistochemistry.

Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected ATP-citrate synthase/ACLY in human pancreas and human prostate tissue.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Minőség

Evaluated by Western Blotting in A549 cell lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected ATP-citrate synthase/ACLY in 10 µg of A549 cell lysate.

Cél megnevezése

~120 kDa observed

Fizikai forma

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Tárolás és stabilitás

Stable for 1 year at 2-8°C from date of receipt.

Egyéb megjegyzések

Concentration: Please refer to lot specific datasheet.

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biztonsági adatok

• Tárolási osztály kódja: 12 - Non Combustible Liquids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable