AB9864R
Anti-NMDAR1 Antibody, clone 1.17.2.6, rabbit monoclonal
clone 1.17.2.6, from rabbit, unconjugated
Szinonimák:
N-methyl-D-aspartate receptor channel, subunit zeta-1, N-methyl-D-aspartate receptor subunit NR1, NMDA receptor 1, glutamate [NMDA] receptor subunit zeta 1, glutamate receptor, ionotropic, N-methyl D-aspartate 1
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(3)
About This Item
UNSPSC kód:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Javasolt termékek
biológiai forrás
rabbit
Minőségi szint
konjugátum
unconjugated
antitest forma
purified immunoglobulin
antitest terméktípus
primary antibodies
klón
1.17.2.6, monoclonal
faj reaktivitás
rat, mouse
faj reaktivitás (homológia által előrejelzett)
human (based on 100% sequence homology)
technika/technikák
immunohistochemistry: suitable
western blot: suitable
izotípus
IgG
NCBI elérési szám
UniProt elérési szám
kiszállítva
wet ice
célzott transzláció utáni módosítás
unmodified
Géninformáció
human ... GRIN1(2902)
mouse ... Grin1(14810)
rat ... Grin1(24408)
Általános leírás
N-methyl-D-aspartate receptor subunit NR1 (NMDAR1) is a multi-pass membrane protein belonging to the glutamate-gated ion channel family and is one of two subunits comprising the tetrameric protein NMDAR localized throughout the brain at excitatory synapses. NMDAR1 is mediated by glycine and is a critical component to excitotoxicity, learning, memory acquisition, synaptic plasticity, and synaptogenesis. It also plays a regulatory role for neuronal functions involving glutamate neurotransmission and the targeting of NMDA receptors on the cell surface. As a glutamate-gated ion channel, NMDAR1 is highly calcium permeable and possesses sensitivity to magnesium in a voltage-dependent manner.
Immunogén
Epitope: Recognizes NMDAR1 at the C-terminus
Linear peptide corresponding to human NMDAR1.
Alkalmazás
Anti-NMDAR1 Antibody, clone 1.17.2.6 detects level of NMDAR1 & has been published & validated for use in WB, IH.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
Western Blot Analysis: 0.1 µg/mL of this antibody from a previous lot detected NMDAR1 on 10 µg of mouse microsomal brain tissue lysate.
Immunohistochemistry Analysis: 1:250 dilution of this antibody from a previous lot detected NMDAR1 in rat cerebellum tissue.
Immunohistochemistry Analysis: 1:250 dilution of this antibody from a previous lot detected NMDAR1 in rat cerebellum tissue.
Minőség
Evaluated by Western Blot in rat brain tissue lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected NMDAR1 on 10 µg of rat brain tissue lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected NMDAR1 on 10 µg of rat brain tissue lysate.
Cél megnevezése
~120 kDa observed
Fizikai forma
Protein A
Purified rabbit monoclonal IgG in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide and 40% Glycerol.
Tárolás és stabilitás
Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Analízis megjegyzés
Control
Rat brain tissue lysate
Rat brain tissue lysate
Egyéb megjegyzések
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Jogi nyilatkozat
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Tárolási osztály kódja
12 - Non Combustible Liquids
WGK
WGK 1
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Analitikai tanúsítványok (COA)
Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.
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Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.
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