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Merck
Összes fotó(2)

Fontos dokumentumok

AB5864

Sigma-Aldrich

Anti-Myelin Basic Protein Antibody

CHEMICON®, rabbit polyclonal

Szinonimák:

MBP

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

UNSPSC kód:
12352203
eCl@ss:
32160702
NACRES:
NA.41
klón:
polyclonal
application:
IHC
faj reaktivitás:
human, rat
technika/technikák:
immunohistochemistry: suitable
citations:
72

Terméknév

Anti-Myelin Basic Protein Antibody, serum, Chemicon®

biológiai forrás

rabbit

Minőségi szint

antitest forma

serum

antitest terméktípus

primary antibodies

klón

polyclonal

faj reaktivitás

human, rat

gyártó/kereskedő neve

Chemicon®

technika/technikák

immunohistochemistry: suitable

UniProt elérési szám

kiszállítva

dry ice

célzott transzláció utáni módosítás

unmodified

Géninformáció

human ... MBP(4155)
rat ... Mbp(24547)

Egyediség

Recognizes Myelin Basic Protein in demyelinated nerve tissues. Immunohistochemistry analysis of lesioned rat spinal cord shows a high level of specificity for this antiserum.

Immunogén

Synthetic peptide corresponding to amino acids 69-86 of the guinea pig protein. Immunogen corresponds to "degraded" Myelin Basic Protein: YGSLPQKSQRSQDENPVV

Alkalmazás

Anti-Myelin Basic Protein Antibody is an antibody against Myelin Basic Protein for use in IH.
Immunohistochemistry: 1:2,000. Immunostains myelin basic protein of abnormal appearing oligodendrocytic processes and cell bodies in demyelinating areas. The antibody recognizes only areas of myelin degeneration when tested in injured spinal cord and lesioned sciatic nerve. It also stains discrete white matter in brain of multiple system atrophy

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Neurodegenerative Diseases

Fizikai forma

Rabbit Serum. Lyophilized, no preservatives. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any residue.
Unpurified

Tárolás és stabilitás

Maintain at -20 to -70°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. Glycerol (1:1) can be added for additional stability.

Analízis megjegyzés

Control
Brain tissue

Egyéb megjegyzések

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Jogi információk

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable


Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

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Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Brian D Clark et al.
Journal of neurotrauma, 20(7), 681-695 (2003-08-12)
Anatomical and physiological changes were evaluated in the median nerves of rats trained to perform repetitive reaching. Motor degradation was evident after 4 weeks. ED1-immunoreactive macrophages were seen in the transcarpal region of the median nerve of both forelimbs by
Role of myelin auto-antigens in pain: a female connection.
Veronica I Shubayev et al.
Neural regeneration research, 11(6), 890-891 (2016-08-03)
Andriy O Glushakov et al.
International journal of molecular sciences, 19(10) (2018-10-17)
Traumatic brain injury (TBI) is associated with long-term disabilities and devastating chronic neurological complications including problems with cognition, motor function, sensory processing, as well as behavioral deficits and mental health problems such as anxiety, depression, personality change and social unsuitability.
Kazuya Takahashi et al.
PLoS medicine, 4(4), e124-e124 (2007-04-12)
In multiple sclerosis, inflammation can successfully be prevented, while promoting repair is still a major challenge. Microglial cells, the resident phagocytes of the central nervous system (CNS), are hematopoietic-derived myeloid cells and express the triggering receptor expressed on myeloid cells
Simon Ngamli Fewou et al.
Glycobiology, 29(9), 657-668 (2019-05-31)
A large body of the literature has demonstrated that the polysialic acid (polySia) modification of the neural cell adhesion molecule (NCAM) is a key regulator of cellular interactions during brain development, maintenance and plasticity. To properly fulfill these functions, polySia

Tudóscsoportunk valamennyi kutatási területen rendelkezik tapasztalattal, beleértve az élettudományt, az anyagtudományt, a kémiai szintézist, a kromatográfiát, az analitikát és még sok más területet.

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