444287

MMP-13, Human, Recombinant, Active

• Szinonimák: Matrix metalloproteinase 13
• UNSPSC kód: 12352202
• NACRES: NA.77

Tulajdonságok

• Forma: liquid
• Minőségi szint: 100
• specifikus aktivitás: ≥50 mU/mg protein
• gyártó/kereskedő neve: Calbiochem^®
• tárolási körülmény: OK to freeze; avoid repeated freeze/thaw cycles
• kiszállítva: wet ice
• tárolási hőmérséklet: −70°C

Leírás

Általános leírás

Recombinant, human MMP-13. MMP-13 is a collagenase-3 enzyme that degrades a range of extracellular matrix proteins, including collagen types I, II, III, IV, IX, X, and XIV, gelatin, aggrecan, perlecan and fibronectin. It is distinguished from other human collagenases by the fact that it effectively degrades type II collagen. The importance of MMP-13 is further strengthened by reports that it is a biomarker for poor prognosis in many carcinomas and other type of cancers.

Kiszerelés

Please refer to vial label for lot-specific concentration.

Figyelmeztetés

Toxicity: Standard Handling (A)

Egység definíció

One unit is defined as the amount of APMA-activated enzyme that will hydrolyze 1µmol MCA-Pro-Leu-Lys-Gly-Leu-DPA-Ala-Arg-NH₂ (Cat. No. 03-32-5032) at 37°C, pH 7.5.

Fizikai forma

In 50 mM HEPES, 10 mM CaCl₂, 20% glycerol, 0.005% Brij^® 35 Detergent, pH 7.5. APMA-free.

Feloldás

Following initial thaw, aliquot and freeze (-70°C).

Egyéb megjegyzések

Freije, M.P.S., et al. 1994. J. Biol. Chem.269,16766.

Jogi információk

Brij is a registered trademark of Croda International PLC

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable