407653

Interleukin-6 Receptor, Soluble, Human, Recombinant, S. frugiperda

• Szinonimák: rhIL-6 sR
• UNSPSC kód: 12352202
• NACRES: NA.42

Tulajdonságok

• Teszt: ≥97% (SDS-PAGE)
• Minőségi szint: 100
• Forma: lyophilized
• gyártó/kereskedő neve: Calbiochem^®
• tárolási körülmény: OK to freeze
• szennyeződések: ≤1 EU/μg Endotoxin
• kiszállítva: ambient
• tárolási hőmérséklet: −70°C

Leírás

Általános leírás

Recombinant, human soluble interleukin-6 receptor expressed in S. frugiperda insect cells. Soluble form of the IL-6 receptor that binds IL-6 and mediates IL-6 signaling through interaction with gp 130. Elevated serum levels of soluble IL-6 receptors have been shown to be associated with a number of pathological states, including multiple myelomas, adult T cell leukemia, interstitial lung infection, and HIV infection.

Recombinant, human soluble interleukin-6 receptor expressed in S. frugiperda insect cells. Soluble form of the IL-6 receptor that binds IL-6 and mediates IL-6 signaling through interaction with gp130. Elevated serum levels of soluble IL-6 receptors have been shown to be associated with a number of pathological states including multiple myelomas, adult T cell leukemia, interstitial lung infection, and HIV infection.

Biokémiai/fiziológiai hatások

ED₅₀= ≥5 ng/ml as measured by its ability to enhance IL-6-induced growth inhibition of mouse M1 myeloid leukemic cells

Figyelmeztetés

Toxicity: Standard Handling (A)

Fizikai forma

Lyophilized from sterile-filtered PBS, 50 µg BSA/µg IL-6 receptor.

Feloldás

Reconstitute to a concentration ≥100 µg/ml with sterile PBS containing at least 0.1% HSA or BSA.

Egyéb megjegyzések

Schobitz, B., et al. 1995. FASEB J. 9, 659.
Yokoyama, A., et al. 1995. Clin. Exp. Immunol. 100, 325.
Suzuki, H., et al. 1993. Eur. J. Immunol. 23, 1078.
Lust, J.A., et al. 1992. Cytokine 4, 96.
Sugita, T., et al. 1990. J. Exp. Med. 171, 2001.
Yamasaki, K., et al. 1988. Science241, 825.

Jogi információk

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable