219370

Coagulation Factor VIIa, Human Plasma

Coagulation Factor VIIa, Human Plasma, is a native coagulation factor VIIa prepared from human Factor VII using human Factor XIIa, which was removed after activation.

• Enzyme Commission szám: 3.4.21.21 (BRENDA, IUBMB)
• UNSPSC kód: 12352202
• NACRES: NA.25

Tulajdonságok

• Minőségi szint: 100
• Teszt: ≥95% (SDS-PAGE)
• form: liquid
• specifikus aktivitás: ≥25,000 PEU/mg protein (clotting assay)
• gyártó/kereskedő neve: Calbiochem^®
• tárolási körülmény: OK to freeze; avoid repeated freeze/thaw cycles
• kiszállítva: wet ice
• tárolási hőmérséklet: −70°C

Leírás

Általános leírás

Native coagulation factor VIIa from human plasma prepared from human Factor VII using human Factor XIIa, which was removed after activation. Factor VIIa provides a crossover point between the extrinsic and intrinsic pathways. Prepared from human Factor VII using Human Factor XIIa.

Native coagulation factor VIIa from human plasma prepared from human Factor VII using human Factor XIIa, which was removed after activation. In the coagulation process, after complexing with tissue factor and membrane phospholipids, Factor VIIa activates Factors IX and X to the enzymatically active Factors IXa and Xa. Provides a crossover point between the extrinsic and intrinsic pathways.

Kiszerelés

Please refer to vial label for lot-specific concentration.

Figyelmeztetés

Toxicity: Standard Handling (A)

Fizikai forma

In 100 mM NaCl, 20 mM Tris-HCl, pH 7.5.

Elkészítési megjegyzés

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Feloldás

Following initial use aliquot and freeze (-70°C).

Analízis megjegyzés

Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma

Egyéb megjegyzések

Broze, G.J. 1994. In Haemostasis and Thrombosis, 3rd Edition(Bloom, et al. Eds.) Churchill Livingstone, Edinburgh, p 349.
Majerus, P.W., et al. 1990. In The Pharmacological Basis of Therapeutics, 8th Edition (Gilman, A.G., et al. Eds.) Pergamon Press, New York, p 1311.

Jogi információk

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Tárolási osztály kódja: 12 - Non Combustible Liquids
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable