07-436-AF488

Anti-monomethyl Histone H3 (Lys4) Antibody, Alexa Fluor^™ 488 Conjugate

0.5 mg/mL, from rabbit

• Szinonimák: Histone H3.1t, H3/t, H3t, H3/g
• UNSPSC kód: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• konjugátum: ALEXA FLUOR^™ 488
• application: ICC
• klón: polyclonal
• faj reaktivitás: human
• technika/technikák: immunocytochemistry: suitable

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• konjugátum: ALEXA FLUOR^™ 488
• antitest forma: purified antibody
• antitest terméktípus: primary antibodies
• klón: polyclonal
• faj reaktivitás: human
• faj reaktivitás (homológia által előrejelzett): vertebrates (based on 100% sequence homology)
• koncentráció: 0.5 mg/mL
• technika/technikák: immunocytochemistry: suitable
• NCBI elérési szám: NM_003493
• UniProt elérési szám: Q16695
• kiszállítva: wet ice
• célzott transzláció utáni módosítás: monomethylation (Lys4)
• Géninformáció: human ... H3C1(8350)

Leírás

Általános leírás

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. Histone proteins are highly post-translationally modified, and Histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Di- and tri-methylation of histone H3 are gene silencing marks, while removal of these marks by the demethylase genes Jmjd1a and Jmjd2c leads to gene activation. This product is a conjugated version of Cat. No. 07-436.

Immunogén

Linear peptide corresponding to Histone H3 monomethylated at Lys4.

Alkalmazás

This Anti-monomethyl Histone H3 (Lys4) Antibody, Alexa Fluor^™ 488 Conjugate is validated for use in ICC for the detection of monomethyl Histone H3 (Lys4).

Minőség

Evaluated by Immunocytochemisty Analysis in HeLa cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected monomethyl Histone H3 (Lys4) in HeLa cells.

Alexa Fluor^™ is a registered trademark of Life Technologies.

Cél megnevezése

~17 kDa observed (Refer to Cat. No. 07-436)

Fizikai forma

Purified rabbit Alexa Fluor^™ 488 conjugated antibody in buffer containing PBS with 15 mg/ml BSA and 0.1% Sodium Azide.

Jogi információk

ALEXA FLUOR is a trademark of Life Technologies

Biztonsági adatok

• Tárolási osztály kódja: 12 - Non Combustible Liquids
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable