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850101P

Avanti

13:0 Lyso PI

1-tridecanoyl-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt), powder

Szinonimák:

PI(13:0/0:0); 110716

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(2)

About This Item

Tapasztalati képlet (Hill-képlet):
C22H46NO12P
CAS-szám:
1246430-02-3
Molekulatömeg:
547.57
UNSPSC kód:
51191904
NACRES:
NA.25

Teszt

>99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC)

Forma

powder

kiszerelés

pkg of 1 × 100 μg (with stopper and crimp cap (850101P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850101P-500ug))

gyártó/kereskedő neve

Avanti Research™ - A Croda Brand 850101P

lipidtípus

phospholipids
cardiolipins

kiszállítva

dry ice

tárolási hőmérséklet

−20°C

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCCCCCCC)=O.[NH4+]

Általános leírás

Lysophosphatidylinositol (LPI), produced by phospholipase A2 is a bioactive lipid.

Alkalmazás

13:0 Lyso PI (1-tridecanoyl-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol) may be used as a nonendogenous phospholipid (PL) standard for the quantitative analysis of PLs. It may also be used as a standard for tandem mass spectrometry analysis of lipid species in human plasma.

Biokémiai/fiziológiai hatások

Increased circulating levels of L-alpha-lysophosphatidylinositol (LPI) are associated with cancer and LPI is a potent ligand for the G-protein-coupled receptor GPR55.
Lysophosphatidylinositol (LPI) is expected to play a vital role in various diseases. Ca2+ channels at the plasma membrane and mitochondrial membrane are controlled by LPI. It can also stimulate various signaling pathways to control several cellular processes. LPI can block the migration of cells.

Kiszerelés

2 mL Amber Serum Vial with Stopper and Crimp Cap (850101P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850101P-500ug)

Jogi információk

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Tárolási osztály kódja

11 - Combustible Solids

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Analitikai tanúsítványok (COA)

Lot/Batch Number

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Dokumentumtár megtekintése

Roberto Piñeiro et al.
Biochimica et biophysica acta, 1821(4), 694-705 (2012-01-31)
Lysophosphatidylinositol (LPI) is a bioactive lipid generated by phospholipase A2 which is believed to play an important role in several diseases. Indeed LPI can affect various functions such as cell growth, differentiation and motility, in a number of cell-types, including
Shuang Song et al.
Food chemistry, 240, 1171-1178 (2017-09-28)
Nuts, a class of fatty natural food, are associated with a series of health benefit. Lipid, which is the most abundant nutrient in nuts, could be one of the major contributors to many beneficial effects. In previous studies, only the
Kevin Huynh et al.
Cell chemical biology, 26(1), 71-84 (2018-11-13)
High-throughput targeted lipid profiling with liquid chromatography-mass spectrometry (LC-MS) has been used extensively to identify associations between plasma lipid species and disease states. Such methods, used to characterize larger clinical cohorts, often suffer from an inability to differentiate isomeric forms
David B Iaea et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1865(4), 158609-158609 (2020-01-10)
STARD4, a member of the evolutionarily conserved START gene family, is a soluble sterol transport protein implicated in cholesterol sensing and maintenance of cellular homeostasis. STARD4 is widely expressed and has been shown to transfer sterol between liposomes as well

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