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472301

Sigma-Aldrich

Dimethyl sulfoxide

Dimethyl sulfoxide

ACS reagent, ≥99.9%

Synonyma:

DMSO

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen

Vybrat velikost

100 ML
1 970,00 Kč
500 ML
5 000,00 Kč
1 L
7 660,00 Kč
2.5 L
20 800,00 Kč
6 X 500 ML
29 600,00 Kč
4 L
32 400,00 Kč
6 X 1 L
45 900,00 Kč

1 970,00 Kč

Na skladěpodrobné informace

Vyžádat hromadnou objednávku
Všechny fotografie(4)

Vybrat velikost

Změnit zobrazení
100 ML
1 970,00 Kč
500 ML
5 000,00 Kč
1 L
7 660,00 Kč
2.5 L
20 800,00 Kč
6 X 500 ML
29 600,00 Kč
4 L
32 400,00 Kč
6 X 1 L
45 900,00 Kč

About This Item

Lineární vzorec:
(CH3)2SO
Číslo CAS:
67-68-5
Molekulová hmotnost:
78.13
Beilstein/REAXYS Number:
506008
EC Number:
200-664-3
MDL number:
MFCD00002089
UNSPSC Code:
12191502
PubChem Substance ID:
329757302
NACRES:
NA.21
grade:
ACS reagent
assay:
≥99.9%
bp:
189 °C (lit.)
vapor pressure:
0.42 mmHg ( 20 °C)

1 970,00 Kč

Na skladěpodrobné informace

Vyžádat hromadnou objednávku

grade

ACS reagent

Quality Level

200

vapor density

2.7 (vs air)

vapor pressure

0.42 mmHg ( 20 °C)

assay

≥99.9%

form

liquid

autoignition temp.

573 °F

expl. lim.

42 %, 63 °F

dilution

(for analytical testing)

impurities

≤0.001 meq/g Titr. acid
≤0.1% water

evapn. residue

≤0.01%

color

clear colorless

refractive index

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

density

1.10 g/mL (lit.)

SMILES string

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

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Související kategorie

General description

Dimethyl sulfoxide is an organosulfur, commonly used as a polar solvent that can dissolve a wide range of polar and non-polar compounds. It is also utilized as a reaction reagent in several well-known processes, including swern oxidation, 2a pfitzner-moffatt oxidation, 2b, and the corey-chaykovsky reaction. [1] [2]

Application

Dimethyl sulfoxide (DMSO) has been used:
  • in the preparation of ethyl 4-[18F]fluorobenzoate.[3]
  • in the culture medium for 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) assay.[4]
  • as a solvent in chemical synthesis.
  • to dissolve and prepare stock solutions of small molecules, drugs, and chemical compounds for various assays and experiments.

Caution

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
For information on dimethyl sulfoxide miscibility, please visit the following link:
Dimethyl Sulfoxide Miscibility/Immiscibility Table

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

Vyberte jednu z posledních verzí:

Osvědčení o analýze (COA)

Lot/Batch Number
SHBS5698
WXBF5111V
WXBF3876V
SHBR7273
SHBR5703

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Sigma-Aldrich

41639

Dimethyl sulfoxide

Methyl sulfoxide ≥99%, FG

Sigma-Aldrich

W387520

Methyl sulfoxide

Shuang Hou et al.
Journal of visualized experiments : JoVE, (52)(52), doi:10-doi:10 (2011-07-07)
Biomolecules, including peptides¹⁻⁹, proteins¹⁰⁻¹¹, and antibodies and their engineered fragments¹²⁻¹⁴, are gaining importance as both potential therapeutics and molecular imaging agents. Notably, when labeled with positron-emitting radioisotopes (e.g., Cu-64, Ga-68, or F-18), they can be used as probes for targeted
The applications of dimethyl sulfoxide as reagent in organic synthesis
Xiao-Feng W, et al.
Advanced Synthesis & Catalysis, 358, 336-352 (2016)
Dimethyl sulfoxide extraction method for the liquid chromatographic analysis of microencapsulated vitamin D3
Richard P J, et al.
Journal of Agricultural and Food Chemistry, 45, 1784-1786 (1997)
P Roy et al.
The FEBS journal, 277(2), 441-452 (2009-12-18)
EVI1 is a nuclear zinc finger protein essential to normal development, which participates in acute myeloid leukaemia progression and transforms Rat1 fibroblasts. In this study we show that enforced expression of Evi1 in Rat1 fibroblasts protects from paclitaxel-induced apoptosis, consistent
Oxidation of alcohols by ?activated? dimethyl sulfoxide. A preparative, steric and mechanistic study.
Omura K and Swern D.
Tetrahedron, 34(11), 1651-1660 (1978)
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Sortimentní položky

Solvent Miscibility Table

Substances are said to be miscible in one another if they dissolve to form a uniform solution. Bookmark or download our miscibility table for common lab solvents.

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Questions

1–10 of 11 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. I know that this substance is of 2 types, with smell and without smell. What type is this?

    1 answer

    1. This is a high purity DMSO. While odor is not a tested specification, high purity products are expected to be odorless. A disagreeable odor is due to the sulfur moiety in the material. DMSO may also contain small amounts of un-reacted Dimethyl Sulfide (DMS). This DMS is generally contributes to a disagreeable odor.

      Helpful?

  4. Can I use this DMSO for cell freezing?Is it sterile

    1 answer

    1. While DMSO is commonly used as a cryoprotectant in cell freezing, this product has not been tested for use in cell culture. This product is also not sterile. See the links below to review the sterile, cell culture tested DMSO product options:
      D2438, DMSO, sterile-filtered, BioPerformance Certified, meets EP & USP testing specifications, suitable for hybridoma
      https://www.sigmaaldrich.com/product/sigma/d2438

      D2650, sterile-filtered, Bioreagent, suitable for hybridoma
      https://www.sigmaaldrich.com/product/sigma/d2650

      Helpful?

  5. Is Dimethyl sulfoxide a sterile product?

    1 answer

    1. No, this product is not considered sterile.  Product Nos. D2560 and D2438 are sterile-filtered.

      Helpful?

  6. Does DMSO have any synthetic utility?

    1 answer

    1. DMSO has been used to oxidize thiols and disulfides to sulfonic acids, hydrolysis of epoxides, thioalkylation of phenols, and oxidation of primary alcohols and halides, and esters of primary alcohols to aldehydes.

      Helpful?

  7. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  8. Where does DMSO come from?

    1 answer

    1. DMSO is known to have been isolated from tree bark in the past. It is now a commericially synthesized solvent.

      Helpful?

  9. Dimethyl sulfoxide (DMSO) should be a liquid.  Why did it arrive as a solid?

    1 answer

    1. DMSO supercools easily, and re-melts slowly at room temperature. The melting point is 16-19 °C. The solidified product can be re-liquefied by warming to room temperature without detriment to the product.

      Helpful?

  10. What is the molarity of DMSO?

    1 answer

    1. DMSO will have a molarity of 14.1M, based on a density of 1.1 g/mL and a molecular weight of 78.13 g/mol.

      Helpful?

1–10 of 11 Questions  

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  1. 1 Ratings-Only Review

Náš tým vědeckých pracovníků má zkušenosti ve všech oblastech výzkumu, včetně přírodních věd, materiálových věd, chemické syntézy, chromatografie, analytiky a mnoha dalších..

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