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V0030000

Valine

European Pharmacopoeia (EP) Reference Standard

Synonyma:

L-Valine, (S)-α-Aminoisovaleric acid, L-2-Amino-3-methylbutanoic acid

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About This Item

Lineární vzorec:
(CH3)2CHCH(NH2)CO2H
Číslo CAS:
Molekulová hmotnost:
117.15
Beilstein/REAXYS Number:
1721136
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

valine

manufacturer/tradename

EDQM

mp

295-300 °C (subl.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(C)[C@H](N)C(O)=O

InChI

1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1

InChI key

KZSNJWFQEVHDMF-BYPYZUCNSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Valine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Osvědčení o analýze (COA)

Lot/Batch Number

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Sigma-Aldrich

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SAFC

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Sigma-Aldrich

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Sigma-Aldrich

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Journal of dermatological science, 75(3), 173-182 (2014-07-13)
Vitamin C (L-ascorbic acid), a known enhancer of collagen deposition, has also been identified as an inhibitor of elastogenesis. Present studies explored whether and how the L-ascorbic acid derivative (+) sodium L-ascorbate (SA) would affect production of collagen and elastic
Thomas D Giles et al.
Lancet (London, England), 383(9932), 1889-1898 (2014-06-03)
The fixed-dose combination of any two antihypertensive drugs from different drug classes is typically more effective in reducing blood pressure than a dose increase of component monotherapy. We assessed the efficacy and safety of a fixed-dose combination of a vasodilating
Xin Zhang et al.
Hypertension (Dallas, Tex. : 1979), 64(1), 87-93 (2014-04-23)
Renovascular hypertension alters cardiac structure and function. Autophagy is activated during left ventricular hypertrophy and linked to adverse cardiac function. The angiotensin II receptor blocker, valsartan, lowers blood pressure and is cardioprotective, but whether it modulates autophagy in the myocardium
K Aaboe et al.
Diabetes, obesity & metabolism, 17(1), 74-81 (2014-09-23)
To examine whether 12 weeks of treatment with a dipeptidyl peptidase-4 (DPP-4) inhibitor, sitagliptin, influences the insulin secretion induced by glucose, glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) during a hyperglycaemic clamp in patients with type 2 diabetes (T2DM).
Growth inhibition as a consequence of antagonism between related amino acids: effect of valine in Escherichia coli K-12.
M De Felice et al.
Microbiological reviews, 43(1), 42-58 (1979-03-01)

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