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B0600000

Benzocaine

European Pharmacopoeia (EP) Reference Standard

Synonyma:

4-Aminobenzoic acid ethyl ester, Ethyl 4-aminobenzoate

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About This Item

Empirický vzorec (Hillův zápis):
C9H11NO2
Číslo CAS:
94-09-7
Molekulová hmotnost:
165.19
Beilstein/REAXYS Number:
638434
MDL number:
MFCD00007892
UNSPSC Code:
41116107
PubChem Substance ID:
329773120
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

benzocaine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCOC(=O)c1ccc(N)cc1

InChI

1S/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3

InChI key

BLFLLBZGZJTVJG-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Benzocaine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Č. produktu
Popis
Stanovení ceny

1054000

Benzocaine, United States Pharmacopeia (USP) Reference Standard

1019767

Aminobenzoate sodium, United States Pharmacopeia (USP) Reference Standard

1265300

Ethyl 4-nitrobenzoate, United States Pharmacopeia (USP) Reference Standard

PHR2094

Diethylamino Hydroxybenzoyl Hexyl Benzoate, Pharmaceutical Secondary Standard; Certified Reference Material

42263

Ethyl 4-formamidobenzoate, reference material

42051

Ethyl 4-[(2-acetyloxybenzoyl)amino]benzoate, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

PHR9020

2-Aminobenzyl alcohol, reference material

PHR9025

Methyl 4-aminobenzoate, reference material

PHR9030

N-Acetylbenzocaine, reference material

PHR2225

Ethyl 4-Nitrobenzoate, Pharmaceutical Secondary Standard; Certified Reference Material

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

233.6 °F

flash_point_c

112 °C

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Osvědčení o analýze (COA)

Lot/Batch Number

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Sigma-Aldrich

F1506

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Sigma-Aldrich

H1758

Hydrochloric acid

H A Cooper
Southern medical journal, 90(9), 946-948 (1997-09-26)
Acute methemoglobinemia is a medical emergency that can rapidly become fatal. A substantial number of drugs, including topical preparations, can precipitate this condition. I report a rare example of severe, acute methemoglobinemia caused by oropharyngeal anesthesia with topical benzocaine spray
L A Linares et al.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 18(3), 267-269 (1990-07-01)
Methemoglobinemia is a condition in which more than 2% of the hemoglobin of the blood has been oxidized to the ferric form, a molecule which is incapable of binding oxygen or carbon dioxide. Clinically, the patient appears lethargic, cyanotic, and
Methemoglobinemia: a complication after fiberoptic orotracheal intubation with benzocaine spray. A case report.
F D Ellis et al.
The Journal of bone and joint surgery. American volume, 77(6), 937-939 (1995-06-01)
L F Rodriguez et al.
The Annals of pharmacotherapy, 28(5), 643-649 (1994-05-01)
To report a case of benzocaine-induced inethemoglobinemia and present a review of the related literature. An 83-year-old man received benzocaine topical anesthesia 600 mg prior to intubation for resection of a thyroid adenoma. The patient became severely cyanotic after induction
Stephan Warnke et al.
Journal of the American Chemical Society, 137(12), 4236-4242 (2015-03-12)
The immediate environment of a molecule can have a profound influence on its properties. Benzocaine, the ethyl ester of para-aminobenzoic acid that finds an application as a local anesthetic, is found to adopt in its protonated form at least two
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