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Merck

53319

Sigma-Aldrich

L-Histidina

≥99.5% (NT), BioUltra

Sinónimos:

NSC 137773, Ácido (S)-2-amino-3-(4-imidazolil)propiónico

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25 G
$74.000
100 G
$247.000

$74.000


Fecha estimada de envío13 de mayo de 2025


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25 G
$74.000
100 G
$247.000

About This Item

Fórmula empírica (notación de Hill):
C6H9N3O2
Número de CAS:
Peso molecular:
155.15
Beilstein:
84088
Número CE:
Número MDL:
Código UNSPSC:
12352209
eCl@ss:
32160406
ID de la sustancia en PubChem:
NACRES:
NA.26

$74.000


Fecha estimada de envío13 de mayo de 2025


Solicitar un pedido a granel

Nombre del producto

L-Histidina, BioUltra, ≥99.5% (NT)

Línea del producto

BioUltra

Nivel de calidad

Ensayo

≥99.5% (NT)

Formulario

powder or crystals

actividad óptica

[α]20/D −39±1°, c = 2% in H2O

impurezas

insoluble matter, passes filter test
≤0.5% foreign amino acids

residuo de ign.

≤0.1% (as SO4)

pérdida

≤0.5% loss on drying, 110 °C

color

white

pH

7.0-8.0 (25 °C, 0.1 M in H2O)

mp

282 °C (dec.) (lit.)
~285 °C (dec.)

solubilidad

H2O: 0.1 M at 20 °C, clear, colorless

trazas de anión

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤100 mg/kg

trazas de catión

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
NH4+: ≤500 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

0.1 M in H2O

Absorción UV

λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.05

cadena SMILES

N[C@@H](Cc1c[nH]cn1)C(O)=O

aplicaciones

detection

InChI

1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1

Clave InChI

HNDVDQJCIGZPNO-YFKPBYRVSA-N

Información sobre el gen

human ... CA1(759) , CA2(760)

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Aplicación

L-Histidine has been used for characterization of ZnO nanorod in an attempt to develop a technique for the ultra-low level detection of l-histidine.[1]

Acciones bioquímicas o fisiológicas

Precursor de la histamina por medio de la histidina descarboxilasa.
L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.[2]
Precursor of histamine by action of histidine decarboxylase.

Otras notas

Amino acid spacing in isotachophoresis on polyacrylamide gels - a critical evaluation[3]; Prevents circular DNA strand cleavage in a xanthine-xanthine oxidase system[4]; Growth requirement of various microorganisms[5].

Aplicación

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Certificados de análisis (COA)

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Visite la Librería de documentos

CRC Handbook of Microbiology, 4, 1-1 (1974)
K Brawn et al.
Acta physiologica Scandinavica. Supplementum, 492, 9-18 (1980-01-01)
An enzymic flux of O2- and H2O2 caused strand breaks in the supercoiled covalently closed circular Col El plasmid. Subnanomolar levels of superoxide levels of superoxide dismutase or of catalase prevented this attack on DNA, signifying that both O2- and
Ultra-Low Level Detection of L-Histidine Using Solution-Processed ZnO Nanorod on Flexible Substrate.
Sasmal M
IEEE Transactions on Nanobioscience, 14(6), 634-640 (2015)
Amino acid spacing in isotachophoresi; on polyacrylamide gel: a critical evaluation.
N Y Nguyen et al.
Analytical biochemistry, 94(1), 202-210 (1979-04-01)
Shweta Singh et al.
Microbial cell factories, 7, 28-28 (2008-10-14)
The large-scale production of G-protein coupled receptors (GPCRs) for functional and structural studies remains a challenge. Recent successes have been made in the expression of a range of GPCRs using Pichia pastoris as an expression host. P. pastoris has a

Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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