53319

L-Histidina

≥99.5% (NT), BioUltra

• Sinónimos: NSC 137773, Ácido (S)-2-amino-3-(4-imidazolil)propiónico
• Fórmula empírica (notación de Hill): C₆H₉N₃O₂
• Número de CAS: 71-00-1
• Peso molecular: 155.15
• Beilstein/REAXYS Number: 84088
• EC Number: 200-745-3
• MDL number: MFCD00064315
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 57651378
• NACRES: NA.26

Propiedades

• Nombre del producto: L-Histidina, BioUltra, ≥99.5% (NT)
• product line: BioUltra
• Quality Level: 200
• assay: ≥99.5% (NT)
• form: powder or crystals
• optical activity: [α]20/D −39±1°, c = 2% in H₂O
• impurities: insoluble matter, passes filter test; ≤0.5% foreign amino acids
• ign. residue: ≤0.1% (as SO₄)
• loss: ≤0.5% loss on drying, 110 °C
• color: white
• pH: 7.0-8.0 (25 °C, 0.1 M in H₂O)
• mp: 282 °C (dec.) (lit.); ~285 °C (dec.)
• solubility: H₂O: 0.1 M at 20 °C, clear, colorless
• anion traces: chloride (Cl^-): ≤100 mg/kg; sulfate (SO₄^2-): ≤100 mg/kg
• cation traces: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; NH₄⁺: ≤500 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 0.1 M in H₂O
• UV absorption: λ: 260 nm A_max: 0.05; λ: 280 nm A_max: 0.05
• SMILES string: N[C@@H](Cc1c[nH]cn1)C(O)=O
• application(s): detection
• InChI: 1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
• InChI key: HNDVDQJCIGZPNO-YFKPBYRVSA-N
• Gene Information: human ... CA1(759) , CA2(760)

Descripción

Application

L-Histidine has been used for characterization of ZnO nanorod in an attempt to develop a technique for the ultra-low level detection of l-histidine.[1]

Biochem/physiol Actions

Precursor de la histamina por medio de la histidina descarboxilasa.

L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.[2]

Precursor of histamine by action of histidine decarboxylase.

Other Notes

Amino acid spacing in isotachophoresis on polyacrylamide gels - a critical evaluation[3]; Prevents circular DNA strand cleavage in a xanthine-xanthine oxidase system[4]; Growth requirement of various microorganisms[5].

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)